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| | Trifluoromethanesulfonyl chloride Basic information |
| | Trifluoromethanesulfonyl chloride Chemical Properties |
| Melting point | -26 °C | | Boiling point | 29-32 °C (lit.) | | density | 1.583 g/mL at 25 °C (lit.) | | vapor pressure | 10.36 psi ( 20 °C) | | refractive index | n20/D 1.334(lit.) | | Fp | 32°C | | storage temp. | 2-8°C | | solubility | Chloroform | | form | Liquid | | color | Clear colorless to faintly colored | | Specific Gravity | 1.583 | | Water Solubility | Hydrolyzes with water. | | Sensitive | Lachrymatory | | BRN | 1812016 | | InChIKey | GRGCWBWNLSTIEN-UHFFFAOYSA-N | | CAS DataBase Reference | 421-83-0(CAS DataBase Reference) |
| Hazard Codes | C | | Risk Statements | 14-34 | | Safety Statements | 26-36/37/39-45 | | RIDADR | UN 3265 8/PG 2 | | WGK Germany | 3 | | F | 10-21 | | Hazard Note | Corrosive/Lachrymatory | | HazardClass | 8 | | PackingGroup | II | | HS Code | 29049090 |
| | Trifluoromethanesulfonyl chloride Usage And Synthesis |
| Chemical Properties | Clear colorless to faintly colored liquid | | Uses | Ru(II) complex-catalyzed trifluoromethylating agent for aromatics and alkenes. | | Application |
Trifluoromethanesulfonyl chloride can be used as:
A trifluoromethylating agent for the fluoroalkylation of heterocycles, arenes, and heteroarenes.
A sulfonating agent for alcohols.
A chlorinating agent for carbanions.
| | Synthesis |
Add 150g (1mol) of trifluoromethanesulfonic acid to the reactor equipped with thermometer, distillation device and mechanical stirrer, slowly add 435mL (6mol) of thionyl chloride under ice bath, and then add the catalyst N,N-dimethyl Formamide 7.36 (0.1 mol), slowly raise the temperature to room temperature, stir for half an hour, continue to heat up to 40°C, continue to stir, react for 12 hours, and then drop to room temperature after the reaction is complete.Subsequently, vacuum distillation was carried out at 110° C. and -0.1 to -0.08 MPa, and at the same time, the temperature was slowly raised to 50° C. to obtain 147 g of trifluoromethanesulfonyl chloride, with a yield of 87.5%.
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| | Trifluoromethanesulfonyl chloride Preparation Products And Raw materials |
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