1-Naphthylacetonitrile

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CAS:132-75-2
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  • 2023-02-26
  • CAS:132-75-2
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1-Naphthylacetonitrile Basic information
Product Name:1-Naphthylacetonitrile
Synonyms:(1-naphthyl)-acetonitril;Acetonitrile, (1-naphthyl)-;alpha-(1-naphthyl)acetonitrile;a-naphthylacetonitrile;ALPHA-NAPHTHYLACETONITRILE;LABOTEST-BB LTBB001326;1-Naphthylene Acetonitrile;1-Naphtylacetonitrile
CAS:132-75-2
MF:C12H9N
MW:167.21
EINECS:205-078-1
Product Categories:Naphthalene series;intermediates;Aromatic Nitriles;Intermediates of Dyes and Pigments
Mol File:132-75-2.mol
1-Naphthylacetonitrile Structure
1-Naphthylacetonitrile Chemical Properties
Melting point 33-35 °C(lit.)
Boiling point 191-194 °C18 mm Hg(lit.)
density 1.1110 (rough estimate)
refractive index n20/D 1.6192(lit.)
Fp >230 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Sparingly), Dichloromethane (Slightly), Methanol (Slightly)
form Liquid After Melting
color Clear yellow to brown
BRN 1101012
CAS DataBase Reference132-75-2(CAS DataBase Reference)
NIST Chemistry Reference1-Naphthaleneacetonitrile(132-75-2)
EPA Substance Registry System1-Naphthaleneacetonitrile (132-75-2)
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38-22
Safety Statements 26-37/39-24/25-37-36
RIDADR 3276
WGK Germany 3
RTECS AM1240000
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29269090
Toxicitymouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03835,
MSDS Information
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1-Naphthylacetonitrile Usage And Synthesis
Chemical PropertiesWhite to yellow solid or melt. Insoluble in water.
Uses2-(Naphthalen-1-yl)acetonitrile is useful for the preparation of tert-Bu benzoates.
PreparationSynthesis of 1-naphthylacetonitrile: 695g of 1-chloromethyl naphthalene, 1500ml of methanol and 475ml of water, 350g of sodium cyanide mixture boiling reflux, stirring the reaction for 2h. 1300ml of methanol was evaporated, cooled, and the reactants were washed with water to neutral to obtain 670-680g of 1-naphthylacetonitrile.
Application1-Naphthylacetonitrile is an organic synthesis intermediate. It is used in the synthesis of 1-naphthylacetate.
Synthesis Reference(s)Chemical and Pharmaceutical Bulletin, 39, p. 3030, 1991 DOI: 10.1248/cpb.39.3030
Tag:1-Naphthylacetonitrile(132-75-2) Related Product Information
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