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N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid

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Company Name: XuZhou Magic Biotechnology Co., Ltd.
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Products Intro: Product Name:2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid
CAS:7365-44-8
Purity:99% Package:1kg;|25kg;|1000kg
Company Name: Hebei Mojin Biotechnology Co., Ltd
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Products Intro: Product Name:2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid
CAS:7365-44-8
Purity:99% Package:25KG
Company Name: Hubei Xindesheng Material Technology Co., Ltd.
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Products Intro: Product Name:2- [[Tri (hydroxymethyl) methyl] amino] Ethanesulfonic acid TES
CAS:7365-44-8
Purity:99% Package:1kg;222.7USD|10kg;194.8USD
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Products Intro: Product Name:2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid
CAS:7365-44-8
Purity:99% Package:1kg;100USD
Company Name: Shanghai Daken Advanced Materials Co.,Ltd
Tel: +86-371-66670886
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Products Intro: Product Name:TES
CAS:7365-44-8
Purity:0.99 Package:5KG;1KG

N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid manufacturers

  • TES
  • TES pictures
  • $5.00 / 25kg
  • 2024-04-29
  • CAS:7365-44-8
  • Min. Order: 1kg
  • Purity: ≥99%
  • Supply Ability: 200mt/year
  • TES
  • TES pictures
  • $0.00 / 1kg
  • 2024-02-20
  • CAS:7365-44-8
  • Min. Order: 1kg
  • Purity: 99.5%
  • Supply Ability: 1000tons

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N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid Basic information
Product Name:N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid
Synonyms:N-[2-HYDROXY-1,1-BIS(HYDROXYMETHYL)ETHYL]TAURINE;N-TRIS(HYDROXYMETHYL)METHYL-2-AMINO-ETHANESULPHONIC ACID;2-[TRIS(HYDROXYMETHYL)METHYL]-2-AMINOETHANE SULFONIC ACID;2-[TRIS(HYDROXYMETHYL)METHYLAMINO]-1-ETHANESULFONIC ACID;2-[[TRIS(HYDROXYMETHYL)METHYL]AMINO]ETHANESULFONIC ACID;2-([2-HYDROXY-1,1-BIS(HYDROXYMETHYL)ETHYL]AMINO)ETHANESULFONIC ACID;2-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-ethanesulfonicaci;Ethanesulfonicacid,2-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-
CAS:7365-44-8
MF:C6H15NO6S
MW:229.25
EINECS:230-906-3
Product Categories:Biochemistry;Good's Buffers;Buffer
Mol File:7365-44-8.mol
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid Structure
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid Chemical Properties
Melting point ~225 °C (dec.)
density 1.260 (estimate)
refractive index 1.5500 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility H2O: 1 M at 20 °C, clear, colorless
form Crystalline Powder
color White
OdorOdorless
PH Range6.8 - 8.2
PH3.5-5.0 (25℃, 1M in H2O)
pka7.5(at 25℃)
Water Solubility SOLUBLE
λmaxλ: 260 nm Amax: 0.055
λ: 280 nm Amax: 0.045
Merck 14,9176
BRN 1957061
InChIKeyJOCBASBOOFNAJA-UHFFFAOYSA-N
CAS DataBase Reference7365-44-8(CAS DataBase Reference)
EPA Substance Registry SystemEthanesulfonic acid, 2-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]- (7365-44-8)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-36-26
WGK Germany 1
TSCA Yes
HS Code 29221980
MSDS Information
ProviderLanguage
2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid English
SigmaAldrich English
ACROS English
ALFA English
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid Usage And Synthesis
Chemical PropertiesWhite/clear crystalline powder
UsesA structural analog to Tris buffer.
UsesN-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid (TES) probably exists in solution as a zwitterion. Because the pKa is 7.4 (physiological pH) this buffer has considerable potential for a variety of biological applications. A buffer using TES free acid can be prepared by titrating the free acid (sc-206102) with sodium hydroxide to the desired pH, using about a half-equivalent of NaOH. Alternatively, solutions of equimolar TES free acid and TES sodium (sc-264384) can be mixed to attain a buffer of the desired pH.  It has been shown to be toxic in vitro, but this toxicity may be due to its ability to form metal chelate complexes that are toxic for cells. TES is a commonly used biological buffering agent.
DefinitionChEBI: N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid is a Good's buffer substance, pKa = 7.5 at 20 ℃. It is a member of ethanolamines, an amino sulfonic acid and a TES. It is functionally related to a taurine. It is a tautomer of a N-tris(hydroxymethyl)methyl-2-ammonioethanesulfonate.
Purification MethodsCrystallise the acid from hot EtOH containing a little water.
N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid Preparation Products And Raw materials
Raw materialsSodium ethylenesulphonate-->Tris(hydroxymethyl)aminomethane-->1-Bromo-2-chloroethane
Tag:N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid(7365-44-8) Related Product Information
Tris-MOPS Buffer,10× Sodium Citrate buffer(0.1mol/L, pH4.5, sterile) CHAPS TRIS hydrochloride PBS Tablets Diammonium 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonate) Phosphate buffer containing Tween 20 (PBS-T tablets) DIPSO 3-[N,N-Bis(hydroxyethyl)amino]-2-hydroxypropanesulphonic acid sodium salt TAPSO 3-[N-Tris(hydroxymethyl)methylamino]-2-hydroxypropanesulfonic acid sodium salt N-[Tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid sodium salt TAPS N-(Tris(hydroxymethyl)methyl)-2-aminoethanesulfonic acid sodium salt N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid Tris(hydroxymethyl)aminomethane N-TRIS(HYDROXYMETHYL)METHYL-2-AMINOETHANESULFONIC ACID-D15 2-([2-HYDROXY-1,1-BIS(HYDROXYMETHYL)ETHYL]AMINO)ETHANESULFONIC ACID HEMISODIUM SALT