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| | 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE Basic information |
| Product Name: | 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE | | Synonyms: | 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE;2-Pyridinecarboxamide,4-(4-amino-3-fluorophenoxy)-N-methyl-;4-(4-Amino-3-fluorophenoxy)pyridine-2-carboxylic acid methylamide;4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide;4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYL-2-PYRIDINECARBOXAMIDE;4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide
EINECS;4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLIMIDE;Regorafenib Intermediate | | CAS: | 757251-39-1 | | MF: | C13H12FN3O2 | | MW: | 261.25 | | EINECS: | 692-721-8 | | Product Categories: | Regorafenib | | Mol File: | 757251-39-1.mol |  |
| | 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE Chemical Properties |
| Melting point | 143 °C | | Boiling point | 459.8±45.0 °C(Predicted) | | density | 1.305 | | vapor pressure | 0Pa at 20℃ | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Chloroform (Slightly), DMSO (Sparingly), Methanol (Slightly) | | form | Solid | | pka | 13.92±0.46(Predicted) | | color | Orange to Dark Red to Brown | | Water Solubility | 190mg/L at 20℃ | | LogP | 1.3 at 25℃ |
| | 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE Usage And Synthesis |
| Chemical Properties | 4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide has the appearance of a white to yellow powder or crystals, which is stable and non-reactive under normal conditions of use, storage and transport. | | Uses | 4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide is a compound used as a reagent to synthesize Regorafenib (R143000), a multikinase inhibitor that is used to treat patients with advanced colorectal cancer. | | Definition | ChEBI: 4-(4-Amino-3-fluorophenoxy)-N-methyl-2-pyridinecarboxamide is an aromatic ether. |
| | 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE Preparation Products And Raw materials |
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