S-烯丙基-L-半胱氨酸

S-烯丙基-L-半胱氨酸

中文名称S-烯丙基-L-半胱氨酸
中文同义词S- 烯丙基别半胱氨酸,蒜氨酸;S- 烯丙基-L-半胱氨酸;烯丙基-L-半胱氨酸;L-S-烯丙基-半胱氨酸;祘氨酸;L-脱氧蒜氨酸;S- 烯丙基别半胱氨酸;S-烯丙基-L-半胱氨酸 1G
英文名称S-ALLYL-L-CYSTEINE
英文同义词S-ALLYL-L-CYSTEINE;(R)-ALLYLTHIO-2-AMINOPROPIONIC ACID;CYSTEINE, S-ALLYL-L-;DEOXYALLIIN;L-DEOXYALLIIN;(L)-3-(ALLYLSULFENYL)-ALANINE;Allylcysteine;(R)-3-(Allylthio)-2-aMinopropanoic acid
CAS号21593-77-1
分子式C6H11NO2S
分子量161.22
EINECS号
相关类别合成;对照品,标准品;定制;小分子抑制剂,天然产物;氨基酸;保护氨基酸;Amino acids methyl、ethyl、t-butyl series;非天然氨基酸;小分子抑制剂;Inhibitors;标准品;试剂盒-Elisa试剂盒
Mol文件21593-77-1.mol
结构式S-烯丙基-L-半胱氨酸 结构式

S-烯丙基-L-半胱氨酸 性质

熔点235-236℃
沸点300℃
密度1.191
FEMA4322 | S-ALLYL-L-CYSTEINE
闪点135℃
储存条件-20°C
溶解度H2O:>10mg/mL
形态粉末
酸度系数(pKa)2.07±0.10(Predicted)
颜色白色至米色
气味 (Odor)0.10% 的丙二醇溶液。烤熟的气味
香型roasted
旋光性 (optical activity)[α]/D -8 to -15°, c = 1 in H2O
JECFA Number1710
稳定性感光
LogP1.31
CAS 数据库21593-77-1(CAS DataBase Reference)

S-烯丙基-L-半胱氨酸 用途与合成方法

S-Allyl-L-cysteine 是一种在大蒜中发现的有机硫化物,拥有多种生物活性,包括神经营养活性,抗癌活性,抗炎活性等。

It is found that S-Allyl-L-cysteine could protect against amyloid-protein (A)-and tunicamycin-induced cell death in differentiated PC12 cells. Simultaneously applied S-Allyl-L-cysteine (1 μM) suppresses the cell death induced by Aβ 25-35 and Aβ 1-40 in a concentration-dependent manner, and neuronal integrity is almost completely retained. Simultaneously applied S-Allyl-L-cysteine significantly decreases the Aβ-induced level of ROS. The TEAC value of S-Allyl-L-cysteine is lower than that of oxidized GSH, and no antioxidant activity is observed. Intracellular GSH levels remains unaffected by treatment of neurons with S-Allyl-L-cysteine for 24 h. Furthermore, the increase in caspase-12 protein expression is suppressed by simultaneously adding 1 μM S-Allyl-L-cysteine . S-Allyl-L-cysteine up to a concentration 1.0 mM does not exhibit any cytotoxic impact on morphology of myoblast and myotubes in culture observed under bright field microscope. TNF treatment leads to a significant decrease in the intracellular CK activity while S-Allyl-L-cysteine pre-treatment to TNF treated myotubes decreases the release of CK in media. S-Allyl-L-cysteine pre-treatment decreases the level of active form of this enzyme in S-Allyl-L-cysteine+TNF group. Similar observations are recorded at mRNA level for caspase-3. These results illustrate that S-Allyl-L-cysteine regulates apoptotic signals via suppressing the transcription and thus protein expression of caspase-3.

安全信息

危险品标志Xi
危险类别码43
安全说明36/37
WGK Germany3
RTECS号HA2466200
海关编码2930.90.9250

MSDS信息

更新日期产品编号产品名称CAS号包装价格
2024/01/25HY-W013573S-Allyl-L-cysteine5 mg250元
2024/01/25HY-W013573S- 烯丙基别半胱氨酸,蒜氨酸
S-Allyl-L-cysteine
21593-77-110mM * 1mLin Water280元

S-烯丙基-L-半胱氨酸 上下游产品信息

"S-烯丙基-L-半胱氨酸"相关产品信息
L-半胱氨酸 GAMMA-谷氨酰-S-烯丙基-L-半胱氨酸 S-烯丙基-D-半胱氨酸 L-GAMMA-谷氨酰烯丙基半胱氨酸 蒜氨酸 普瑞司坦 N-乙酰基-S-法呢基-L-半胱氨酸甲酯 S-烯丙基-L-半胱氨酸
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