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| SIB 1757 Basic information |
Product Name: | SIB 1757 | Synonyms: | SIB 1757;SIB-1757 6-METHYL-2-(PHENYLAZO)-3-PYRIDINOL;6-METHYL-2-(PHENYLAZO)-3-PYRIDINOL;6-Methyl-2-[(E)-phenyldiazenyl]pyridin-3-ol;(E)-6-Methyl-2-(phenyldiazenyl)pyridin-3-ol;6-methyl-2-[(E)-phenyldiazenyl]pyridin-3;3-Pyridinol, 6-methyl-2-(2-phenyldiazenyl)-;SIB-1757,mGluR,SIB1757,Metabotropic glutamate receptors,inhibit,Inhibitor,SIB 1757 | CAS: | 31993-01-8 | MF: | C12H11N3O | MW: | 213.24 | EINECS: | | Product Categories: | Glutamate receptor | Mol File: | 31993-01-8.mol | |
| SIB 1757 Chemical Properties |
storage temp. | Store at RT | solubility | DMSO (Slightly), Methanol (Slightly) | form | crystalline | color | red |
Hazard Codes | Xi | Risk Statements | 36/37/38 | Safety Statements | 26-36 | WGK Germany | 3 |
| SIB 1757 Usage And Synthesis |
Uses | SIB 1757 is an antagonist for mGluR-5. | Definition | ChEBI: 6-methyl-2-(phenylhydrazinylidene)-3-pyridinone is a member of phenylhydrazines. | Biological Activity | A highly selective antagonist for the mGlu 5 metabotropic glutamate receptor subtype; displays an IC 50 value of 0.4 μ M at hmGlu 5 compared with > 30 μ M at hmGlu 1b , hmGlu 2 , hmGlu 4 , hmGlu 6 , hmGlu 7 and hmGlu 8 . |
| SIB 1757 Preparation Products And Raw materials |
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