| Company Name: |
Guangzhou PI PI Biotech Inc
|
| Tel: |
+86-020-81716320 +86-13602409664 |
| Email: |
Sales@pipitech.com |
| Products Intro: |
Product Name:Ritodrine
CAS:26652-09-5
Purity:90%+ Package:10mg;USD|25mg;USD|50mg;USD
|
| Company Name: |
LGM Pharma
|
| Tel: |
1-(800)-881-8210 |
| Email: |
inquiries@lgmpharma.com |
| Products Intro: |
Product Name:Ritodrine
CAS:26652-09-5
Purity:Typically NLT 98%
|
- RITODRINE
-
- $1.10 / 1g
-
2024-04-17
- CAS:26652-09-5
- Min. Order: 1g
- Purity: 99.0% min
- Supply Ability: 100 tons min
- Ritodrine
-
- $0.00 / 10mg
-
2024-04-10
- CAS:26652-09-5
- Min. Order: 10mg
- Purity: 90%+
- Supply Ability: 10g
- RITODRINE USP/EP/BP
-
- $1.10 / 1g
-
2021-06-02
- CAS:26652-09-5
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100Tons min
|
| | RITODRINE Basic information |
| Product Name: | RITODRINE | | Synonyms: | 4-hydroxy-alpha-(1-((2-(4-hydroxyphenyl)ethyl)amino)ethyl)-benzenemethano(;4-hydroxy-alpha-(1-((2-(4-hydroxyphenyl)ethyl)amino)ethyl)benzenemethanol(r*;erythro-p-hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)benzylalcohol;RITODRINE;Benzenemethanol, 4-hydroxy-a-[(1R)-1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]-, (aS)-rel- (9CI);Benzenemethanol, 4-hydroxy-a-[1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]-, (R*,S*)-;Benzyl alcohol, p-hydroxy-a-[1-[(p-hydroxyphenethyl)amino]ethyl]-, erythro- (8CI);(1R,2S)-1-(4-Hydroxyphenyl)-2-[(4-hydroxyphenethyl)amino]-1-propanol | | CAS: | 26652-09-5 | | MF: | C17H21NO3 | | MW: | 287.35 | | EINECS: | 247-879-9 | | Product Categories: | | | Mol File: | 26652-09-5.mol |  |
| | RITODRINE Chemical Properties |
| Melting point | 88-90 °C | | Boiling point | 512.3±45.0 °C(Predicted) | | density | 1.213±0.06 g/cm3(Predicted) | | pka | pKa 9.0 (Uncertain) |
| | RITODRINE Usage And Synthesis |
| Description | Ritodrine, 4-hydroxy-α-[1-[(4′-hydroxyphenethyl)amino]ethyl]benzylic alcohol
(11.1.19), differs slightly from epinephrine, and in the given example only one hydroxyl
group has been added to the aromatic ring of the phenylethylamino region of classic sympathomimetics. The second major difference between the examined series is the replacement of
the traditionally terminal iso-propyl or tert-butylamine region with a p-hydroxyphenylethylamine. Finally, the third difference is the presence of a methyl group at the α-atom of the
phenylethylamine region of sympathomimetics, which makes it similar to isoetharine. | | Uses | Relaxant (smooth muscle). | | Uses | Ritodrine is a selective β2-adrenoreceptor stimulant, predominantly of the urino-genital
system. It is used as a tocolytic agent for problems associated with premature miscarriages, and only in specialized medical facilities. | | Definition | ChEBI: (1S,2R)-ritodrine is a 4-[2-[[1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]phenol that has (1S,2R)-configuration. It is an enantiomer of a (1R,2S)-ritodrine. | | General Description | Ritodrine is a selective β2-agonist that wasdeveloped specifically for use as a uterine relaxant. Its uterineinhibitory effects are more sustained than its effects onthe cardiovascular system, which are minimal comparedwith those caused by nonselective β-agonists. The cardiovasculareffects usually associated with its administrationare mild tachycardia and slight diastolic pressure decrease.Usually, it is administered initially by intravenous infusionto stop premature labor and subsequently it may be givenorally. | | Clinical Use | Ritodrine is a selective β2-agonist that is used exclusively for relaxing uterine muscle and inhibiting the contractions of premature labor.
Terbutaline, in addition to its use as a bronchodilator, also has been used for halting the contractions of premature labor. | | Synthesis | Ritodrine is synthesized from 4-benzyloxypropiophenone, which undergoes bromination into
4-benzyloxy-|á-bromopropiophenone (11.1.17). This is reacted with 2-(4-benzyloxyphenyl)ethylamine, forming an intermediate product (11.1.18), which undergoes
further debenzylation by hydrogen using a palladium catalyst, giving ritodrine (11.1.19)
[24,25]. 
|
| | RITODRINE Preparation Products And Raw materials |
|