ChemicalBook > Product Catalog >Biochemical Engineering >Nucleoside drugs >Deoxynucleotides and their analogs >5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine

5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine

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CAS:68892-41-1
Purity:98%HPLC Package:Customized Packaging
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CAS:68892-41-1
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CAS:68892-41-1
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CAS:68892-41-1
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Products Intro: Product Name:5-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine
CAS:68892-41-1
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5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine manufacturers

  • N2-iBu-DMT-dG
  • N2-iBu-DMT-dG pictures
  • $0.00 / 1KG
  • 2024-09-23
  • CAS:68892-41-1
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 1000kgs per Month
  • iBu-DMT-dG
  • iBu-DMT-dG pictures
  • $0.00 / 1kg
  • 2023-04-04
  • CAS:68892-41-1
  • Min. Order: 1kg
  • Purity: 98%
  • Supply Ability: 500kg per month
5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine Basic information
Product Name:5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine
Synonyms:5'-O-DIMETHOXYTRITYL-N-ISOBUTYRYL-DEOXYGUANOSINE;5'-O-(4,4'-DIMETHOXYTRITYL)-N2-ISOBUTYRYL-2'-DEOXYGUANOSINE;N(sup 2)-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxygu;N-[9-[(2R,4S,5R)-5-[[Bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-6-oxo-3H-purin-2-yl]-2-methylpropanamide;2'-Deoxy-5'-O-(4,4'-dimethoxytrityl)-N-isobutyrylguanosine;5'-O-(4,4'-Dimethoxytrityl)-N-isobutyryl-2'-deoxyguanosine;N-[9-[5-O-(4,4'-Dimethoxytrityl)-2-deoxy-β-D-ribofuranosyl]-6-oxo-1,6-dihydro-9H-purine-2-yl]isobutyramide;DMT-i-bu-dG
CAS:68892-41-1
MF:C35H37N5O7
MW:639.7
EINECS:272-615-4
Product Categories:Nucleosides, Nucleotides & Related Reagents;Biochemistry;Nucleosides and their analogs;Organics;PNS;Modified(deoxy)nucleoside
Mol File:68892-41-1.mol
5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine Structure
5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine Chemical Properties
Melting point ~150 °C (dec.)(lit.)
Boiling point 671.92°C (rough estimate)
density 1.2353 (rough estimate)
refractive index 1.7500 (estimate)
storage temp. Inert atmosphere,2-8°C
solubility soluble in Methanol
form powder to crystal
pka9.16±0.20(Predicted)
color White
Water Solubility 2.4mg/L at 20℃
InChIKeyRMQXDNUKLIDXOS-PTIWCXHYNA-N
SMILESC(OC[C@@H]1[C@@H](O)C[C@H](N2C=NC3C(=O)NC(NC(=O)C(C)C)=NC2=3)O1)(C1=CC=CC=C1)(C1C=CC(OC)=CC=1)C1=CC=C(OC)C=C1 |&1:3,4,7,r|
LogP2.98 at 20℃
CAS DataBase Reference68892-41-1(CAS DataBase Reference)
EPA Substance Registry SystemGuanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)- (68892-41-1)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
1-3-10
HS Code 29349990
MSDS Information
ProviderLanguage
5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine English
SigmaAldrich English
ACROS English
5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine Usage And Synthesis
Uses N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine (5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine) can be used as fluorescent hydrogel with high intensity.
Flammability and ExplosibilityNot classified
Synthesis 2N-Isobutyryl deoxyguanosine (B5-I) was dried by co-evaporation with dry pyridine three times. To a stirred suspension of dry (B5-I) (14.15 mmol) in pyridine (100 mL), a solution of dimetoxytrityl chloride (14.8 mmol) in pyridine (30 mL) was added dropwise over 60 min. The reaction mixture was left for 4 h at room temperature, cooled to 0 C. by immersion in an ice water bath, quenched with 5% NaHCO3 (100 mL), and extracted with ethyl acetate (3×100 mL). The organic fractions were pooled, dried over magnesium sulfate, and concentrated in a vacuum, and the residue was co-evaporated with toluene. The gum oil residue was dissolved in a minimum amount of methylenechloride and added dropwise to a mixture of ethyl and petroleum ether (2000 mL 75/25) with stirring. After 20 min, pure 5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine precipitated from the solution and was filtered off and dried. Yield: 75%
5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine Preparation Products And Raw materials
Preparation ProductsDG-ME PHOSPHONAMIDITE-->IBU-DMT-DEOXYGUANOSINE SUCCINIC ACID
Tag:5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine(68892-41-1) Related Product Information
5'-O-Dimethoxytrityl-deoxythymidine 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine 2'-Deoxyguanosine N2-Isobutyryl-2'-deoxyguanosine Isobutyramide N2-ISOBUTYRYL-2'-DEOXYGUANOSINE DMT-dG(ib) Phosphoramidite 5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine 5'-O-(4,4'-DIMETHOXYTRITYL)-N2-ISOBUTYRYL-2'-DEOXYGUANOSINE-3'-(METHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE 5'-O-(DIMETHOXYTRITYL)-8-HYDROXY-N2-ISOBUTRYL-2'-DEOXYGUANOSINE IBU-DMT-DEOXYGUANOSINE SUCCINIC ACID 5'-DMT-RIBO GUANOSINE (N-IBU) 2'-Deoxyguanosine monohydrate 5'-O-FDMT-N2-ISOBUTYRYL-2'-DEOXYGUANOSINE CEP 3'-DMT-DG(IBU)-SUC-CPG 5'-DMT-DG(IBU)-SUC-CPG N2-(ISOBUTYRYL)-5'-O-(DIMETHOXYTRITYL)-2'-O-(T-BUTYLDIMETHYLSILYL)-GUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE 5'-DIMETHOXYTRITYL-N2-ISOBUTYRYL-2'-(2-METHOXYETHYL)GUANOSINE