| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037 |
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3bsc@sina.com |
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Product Name:Ro 19-4603;5,6-Dihydro-5-Methyl-6-oxo-4H-iMidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylicacid1,1-diMethylethylester
CAS:99632-94-7
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
HangZhou YuHao Chemical Technology Co., Ltd.
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| Tel: |
0571-82693216 |
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info@yuhaochemical.com |
| Products Intro: |
Product Name:5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A]THIENO[2,3-F][1,4]DIAZEPINE-3-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER
CAS:99632-94-7
Purity:98% Package:1g; 10g; 100g
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| Company Name: |
EMMX Biotechnology LLC
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888-539-0666 |
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info@emmx.com |
| Products Intro: |
Product Name:Ro 19-4603
CAS:99632-94-7
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| Company Name: |
BOC Sciences
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info@bocsci.com |
| Products Intro: |
Product Name:Ro 19-4603
CAS:99632-94-7
Purity:≥99% by HPLC Remarks:Ro 19-4603 is a novel potent partial inverse agonist of benzodiazepine (BZ) receptors. Ro19-4603 binds with high affinity to both diazepam-sensitive (DS) and diazepam-insensitive (DI) GABAA receptors
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| | 5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A]THIENO[2,3-F][1,4]DIAZEPINE-3-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER Basic information |
| Product Name: | 5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A]THIENO[2,3-F][1,4]DIAZEPINE-3-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER | | Synonyms: | RO 19-4603;5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A]THIENO[2,3-F][1,4]DIAZEPINE-3-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER;5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylicacid1,1-dimethylethylester;4H-Imidazo[1,5-a]thieno[2,3-f][1,4]diazepine-3-carboxylic acid, 5,6-dihydro-5-methyl-6-oxo-, 1,1-dimethylethyl ester;Ro 194603,Ro 19 4603 | | CAS: | 99632-94-7 | | MF: | C15H17N3O3S | | MW: | 319.38 | | EINECS: | | | Product Categories: | | | Mol File: | 99632-94-7.mol | ![5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A]THIENO[2,3-F][1,4]DIAZEPINE-3-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER Structure](CAS/GIF/99632-94-7.gif) |
| | 5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A]THIENO[2,3-F][1,4]DIAZEPINE-3-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER Chemical Properties |
| storage temp. | Store at RT | | solubility | <31.94mg/ml in ethanol; <31.94mg/ml in DMSO |
| | 5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A]THIENO[2,3-F][1,4]DIAZEPINE-3-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER Usage And Synthesis |
| Uses | Ro 19-4603 is a novel benzodiazepine inverse agonist. | | Definition | ChEBI: Ro 19-4603 is an organonitrogen heterocyclic compound, an organosulfur heterocyclic compound and a tert-butyl ester. | | Biological Activity | Benzodiazepine inverse agonist. Binds with high affinity to both diazepam-sensitive (DS) and diazepam-insensitive (DI) GABA A receptors (K i values are ~ 0.2 and ~ 2.6 nM for DS and DI receptors respectively). Antagonizes effects of ethanol on locomotor behavior and suppresses ethanol intake in alcohol-preferring rats. |
| | 5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A]THIENO[2,3-F][1,4]DIAZEPINE-3-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER Preparation Products And Raw materials |
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