GLUCOPSYCHOSINE manufacturers
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| | GLUCOPSYCHOSINE Basic information |
| Product Name: | GLUCOPSYCHOSINE | | Synonyms: | sphingosylbeta-glucoside;2-(2-amino-3-hydroxy-octadec-4-enoxy)-6-(hydroxymethyl)oxane-3,4,5-triol;1-β-D-Glucosylsphingosine;(2S,3R,4E)-2-AMino-3-hydroxy-4-octadecenyl β-D-Glucopyranoside;2-AMino-3-hydroxy-4-octadecenyl β-D-Glucopyranoside;Glucosyl-C18-sphingosine;D-glucosyl-1-1'-D-erythro-sphingosine;b-D-Glucopyranosyl-1,1’-2’-amino-4’-octadecene-1’,3’-diol Synonym:Glucosylsphingosine | | CAS: | 52050-17-6 | | MF: | C24H47NO7 | | MW: | 461.63 | | EINECS: | | | Product Categories: | Amino Acids & Derivatives;Protein Kinase Inhibitors and Activators | | Mol File: | 52050-17-6.mol |  |
| | GLUCOPSYCHOSINE Chemical Properties |
| Melting point | >136°C (dec.) | | Boiling point | 664.3±55.0 °C(Predicted) | | density | 1.14±0.1 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) | | form | Solid | | pka | 11.74±0.45(Predicted) | | color | White to Off-White | | BRN | 4333674 | | Stability: | Hygroscopic |
| Hazard Codes | B | | WGK Germany | 3 | | HS Code | 2932990090 |
| | GLUCOPSYCHOSINE Usage And Synthesis |
| Chemical Properties | Light Brown Residue | | Uses | A sphingosine derivative. A sphingolipid compound found in the the umbilical cord artery of women with preeclampsia. | | Uses | Glucosyl(β) Sphingosine (d18:1) or D-glucosyl-β1-1′-D-erythro-sphingosine may be used:
- to screen lipids that rapidly and reversibly alter?transepithelial?electrical resistance (TER) or tight junction (TJ) permeability in epithelial tissue
- as a standard for the quantification of glucosyl sphingosine?in Gaucher patients using liquid chromatography electrospray ionization tandem mass spectrometric (LC/ESI-MS/MS)
- as an internal standard for the quantification of lysoglucosylceramide in plasma for Gaucher disease using liquid chromatography with tandem mass spectrometry (LC-MS/MS)
| | Definition | ChEBI: Beta-D-glucosylsphingosine is d-Glucosylsphingosine in which the anomeric configuration of the glucosyl moiety is beta. It is a D-glucosylsphingosine and a beta-D-glucoside. It is a conjugate base of a beta-D-glucosylsphingosine(1+). | | General Description | Glucosyl?sphingosine is a lyso derivative of glucosylceramide (GlcCer). | | Biochem/physiol Actions | Glucosyl?sphingosine is a potential biomarker for Gaucher′s?disease.?It modulates?Ca2+?release?in the brain?microsomes. |
| | GLUCOPSYCHOSINE Preparation Products And Raw materials |
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