- 4-tert-Octylphenol
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- $6.00 / 1KG
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2024-01-18
- CAS:140-66-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- 4-tert-Octylphenol
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- $2.50 / 1kg
-
2024-01-18
- CAS:140-66-9
- Min. Order: 1kg
- Purity: 99%+
- Supply Ability: 1000kg
- 4-tert-Octylphenol
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- $0.00 / 25KG
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2023-09-01
- CAS:140-66-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
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| | 4-tert-Octylphenol Basic information |
| | 4-tert-Octylphenol Chemical Properties |
| | 4-tert-Octylphenol Usage And Synthesis |
| Chemical Properties | white powder | | Uses | 4-tert-Octylphenol (4t-OP) is used in manufacturing processes as an intermediate in the generation of surfactants, synthetic rubber additives, or resins. 4t-OP is also used to manufacture alkylphenol ethoxylates. It is found mainly in detergents, cleaning products, and emulsifiers and less frequently in paints, personal care products, pesticides, paper, pulp, and textiles. | | Definition | ChEBI: 4-tert-Octylphenol is an alkylbenzene. | | General Description | 4-tert-Octylphenol is a potential environmental pollutant and it exhibits toxic and estrogenic effects on mammalian cells. It binds to estrogen receptors and exerts estrogenic actions in vitro. The transformation of the 4-tert-octylphenol upon irradiation at 253.7nm and by hydroxyl radicals generated by the photolysis (λexc = 253.7nm) of hydrogen peroxide in aqueous solution has been studied. | | Health effects | 4-tert-octylphenol (OP) is an endocrine-disrupting chemical that causes harmful effects to human health.a common environmental pollutant showing weak estrogenic effects. 4-tert-Octylphenol has been shown to cause harm to the male reproductive system of vertebrates.
High doses of several alkylphenols, including 4- tert-octylphenol, have altered estrogenic effects, including sex hormone levels, estrus cycles, reproductive outcomes, neonatal sexual development, as well as impaired production of steroid hormone and testicular atrophy. | | Environmental Fate | Studies have shown that 4t-OP will adsorb to sediments. | | Purification Methods | Crystallise the phenol from n-hexane and/or distil it in a vacuum. [Beilstein 6 III 2051, 6 IV 3484.] | | Toxicity evaluation | 4t-OP has been shown to be an estrogen receptor (ER) agonist.
Estrogenic effects of 4t-OP have been demonstrated in human
cells, with 4t-OP displacing the natural estrogen 17b estradiol
from its receptor, and 4t-OP inducing cell proliferation in
estrogen-dependent cell proliferation assays. In vivo confirmation
of 4t-OP’s estrogenicity has been confirmed with the uterotrophic
assay. |
| | 4-tert-Octylphenol Preparation Products And Raw materials |
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