(S)-(-)-5-FLUOROWILLARDIINE manufacturers
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| | (S)-(-)-5-FLUOROWILLARDIINE Basic information |
| Product Name: | (S)-(-)-5-FLUOROWILLARDIINE | | Synonyms: | 5-fluorowillardiine;(S)-(-)-5-FLUOROWILLARDIINE;(S)-(-)-ALPHA-AMINO-5-FLUORO-3,4-DIHYDRO-2,4-DIOXO-1(2H)PYRIDINEPROPANOIC ACID;WILLARDIINE, S(-)-5-FLUORO POTENT AMPA/K AINATE A;(S)-(-)-alpha-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimmidinepropanoic acid;(S)-(-)-α-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)pyridinepropanoicacid;(αS)-α-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid;3-(5-fluorouracil-1-yl)-L-alanine | | CAS: | 140187-23-1 | | MF: | C7H8FN3O4 | | MW: | 217.15 | | EINECS: | | | Product Categories: | Glutamate receptor;Glutamate | | Mol File: | 140187-23-1.mol |  |
| | (S)-(-)-5-FLUOROWILLARDIINE Chemical Properties |
| Melting point | >209°C (dec.) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Aqueous Acid (Slightly) | | form | Solid | | color | White to Pale Beige |
| | (S)-(-)-5-FLUOROWILLARDIINE Usage And Synthesis |
| Uses | (S)-(-)-5-Fluorowillardiine is a potent and selective AMPA receptor agonist at hGluR1 and hGluR2 (1,2). | | Definition | ChEBI: An alanine derivative that is L-alanine bearing a 5-fluorouracil-1-yl substituent at position 3. A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (Ki = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and
hGluR5 respectively). | | Biological Activity | A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (K i = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively). Also available as part of the AMPA Receptor Tocriset™ . |
| | (S)-(-)-5-FLUOROWILLARDIINE Preparation Products And Raw materials |
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