| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:Oxodipine
CAS:90729-41-2
Purity:99.22% Package:5 mg；1 mg；10 mg；100 mg；25 mg；50 mg；；
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| Company Name: |
Shaanxi Xihua Chemical Industry Co., Ltd
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| Tel: |
17691182729 15529505138 |
| Email: |
1021@dideu.com |
| Products Intro: |
Product Name:5-O-ethyl 3-O-methyl 4-(1,3-benzodioxol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
CAS:90729-41-2
Purity:98 Package:25kg
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| Company Name: |
Leancare Ltd.
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| Tel: |
+33 962096793 |
| Email: |
enquiry@leancare.co.uk |
| Products Intro: |
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| Company Name: |
2A PharmaChem USA
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| Tel: |
(630) 737-0988 |
| Email: |
sales@2apharmachem.com |
| Products Intro: |
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| | Oxodipine Basic information |
| Product Name: | Oxodipine | | Synonyms: | Oxodipine;5-O-ethyl 3-O-methyl 4-(1,3-benzodioxol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;3,5-Pyridinedicarboxylic acid, 4-(1,3-benzodioxol-4-yl)-1,4-dihydro-2,6-dimethyl-, 3-ethyl 5-methyl ester | | CAS: | 90729-41-2 | | MF: | C19H21NO6 | | MW: | 359.37 | | EINECS: | | | Product Categories: | | | Mol File: | 90729-41-2.mol |  |
| | Oxodipine Chemical Properties |
| Boiling point | 470.0±45.0 °C(Predicted) | | density | 1.247±0.06 g/cm3(Predicted) | | pka | 2.98±0.70(Predicted) |
| | Oxodipine Usage And Synthesis |
| Enzyme inhibitor | This dihydropyridine-class calcium ion blocker (FW = 359.37 g/mol; CAS 90729-41-2), also known as 4-(1,3-benzodioxol-4-yl)-2,6-dimethyl-1,4- dihydropyridine-3,5-dicarboxylic acid O3 -ethyl,O5 -methyl ester, greatly depresses KCl-induced contraction of rabbit aorta and also decreases the contractile force of rat ventricular strips, the latter with lower potency. Oxodipine markedly shortens cardiac action potentials, and, in rat cultured neonatal ventricular myocytes, oxodipine decreases the L-type Ca2+ current (ICaL) with IC50 of 0.24 μM and is also an effective blocker of T-type Ca2+ current (ICaT) than elgodipine (IC50 = 0.41 μM). |
| | Oxodipine Preparation Products And Raw materials |
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