|
|
| | Methyl 3-hydroxy-4-methoxybenzoate Basic information |
| | Methyl 3-hydroxy-4-methoxybenzoate Chemical Properties |
| Melting point | 64-67 °C (lit.) | | Boiling point | 102 °C(Press: 0.1 Torr) | | density | 1.216±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | form | powder to crystal | | pka | 9.15±0.10(Predicted) | | color | Light yellow to Brown | | LogP | 1.750 (est) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29189990 |
| | Methyl 3-hydroxy-4-methoxybenzoate Usage And Synthesis |
| Chemical Properties | Off-white to beige crystalline powder | | Uses | Methyl 3-hydroxy-4-methoxybenzoate may be used as starting reagent in the novel synthesis of gefitinib. Synthesis involves the alkylation of starting material, followed by nitration, reduction, cyclization, chlorination and two successive amination reactions. It may be used as starting reagent in the synthesis of methyl 5-(benzo[d][1,3]dioxol-5-yl)-4-methoxy-2-nitrobenzoate. |
| | Methyl 3-hydroxy-4-methoxybenzoate Preparation Products And Raw materials |
|