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| | DULCITOL Basic information |
| | DULCITOL Chemical Properties |
| Melting point | 164-166 °C (lit.) | | Boiling point | 275-280 °C (1 mmHg) | | density | 1.1382 (rough estimate) | | refractive index | 1.5510 (estimate) | | storage temp. | 2-8°C | | solubility | Chloroform (Slightly), Methanol (Slightly, Heated) | | form | Crystalline Powder | | color | yellow to tan | | BRN | 18991 | | LogP | 5.003 (est) | | CAS DataBase Reference | 6051-87-2(CAS DataBase Reference) |
| | DULCITOL Usage And Synthesis |
| Chemical Properties | SLIGHTLY BEIGE CRYSTALLINE POWDER | | Uses | beta-Naphthoflavone is a Cytochrome P450 enzyme system inducer. It can also be used in biological study of novel dual-color luciferase reporter assay for simultaneous detection of estrogen and aryl hydrocarbon receptor activation. | | Definition | ChEBI: An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone. | | General Description | β-Naphthoflavone is a polyaromatic hydrocarbon. | | Biochem/physiol Actions | β-Naphthoflavone (BNF) is an exogenous ligand for aryl hydrocarbon receptor (AhR) in humans. It is an inducer of phase I detoxification enzymes (CYPs) and phase II enzymes (UDP-GTs) and NAD(P)H-dependent quinone oxyreductase-1(NQO1). It also induces cytochrome P450 (Cyp1a). BNF represses the expression of Duchenne muscular dystrophy gene, dystrophin (Dp)71 by altering the binding of the transcription factors. |
| | DULCITOL Preparation Products And Raw materials |
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