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| | 1,4-Dihydro-2,6-dimethyl-4-(2',3'-dichlorophenyl)-5-carboxy methyl-3-pyridinecarboxylic acid Basic information |
| Product Name: | 1,4-Dihydro-2,6-dimethyl-4-(2',3'-dichlorophenyl)-5-carboxy methyl-3-pyridinecarboxylic acid | | Synonyms: | 1,4-Dihydro-2,6-dimethyl-4-(2',3'-dichlorophenyl)-5-carboxy methyl-3-pyridinecarboxylic acid;3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-diMethyl-, 3-Methyl ester;Desethyl Felodipine;1,4-Dihydro-2,6-diMethyl-4-(2',3'-dichlorophenyl)-5-carboxy Meth;4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid monomethyl ester;4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid 3-methyl ester;Monomethyl Felodipine;-2,6-dimethyl-1,4-dihydropyridine-3-carboxylic acid | | CAS: | 123853-39-4 | | MF: | C16H15Cl2NO4 | | MW: | 356.2 | | EINECS: | | | Product Categories: | | | Mol File: | 123853-39-4.mol |  |
| | 1,4-Dihydro-2,6-dimethyl-4-(2',3'-dichlorophenyl)-5-carboxy methyl-3-pyridinecarboxylic acid Chemical Properties |
| Melting point | 197-200°C | | Boiling point | 483.0±45.0 °C(Predicted) | | density | 1.375±0.06 g/cm3 (20 ºC 760 Torr) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 1.65±0.70(Predicted) | | color | Pale Yellow to Pale Beige |
| | 1,4-Dihydro-2,6-dimethyl-4-(2',3'-dichlorophenyl)-5-carboxy methyl-3-pyridinecarboxylic acid Usage And Synthesis |
| Uses | Desethyl Felodipine is an impurity in the synthesis of Felodipine (F232375), a dihydropyridine calcium channel blocker. |
| | 1,4-Dihydro-2,6-dimethyl-4-(2',3'-dichlorophenyl)-5-carboxy methyl-3-pyridinecarboxylic acid Preparation Products And Raw materials |
| Raw materials | 4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester-->Felodipine 3,5-DiMethyl Ester-->Methyl 2-(2,3-dichlorobenzylidine)acetoacetate-->2,3-Dichlorobenzaldehyde | | Preparation Products | 4-(2,3-Dichlorophenyl)-2,6-diMethyl-1,4-dihydropyridine-3,5-dicarboxylic acid |
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