| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:GDC-0575 dihydrochloride
CAS:1657014-42-0
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| | EOS-62353 Basic information |
| | EOS-62353 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO : 65 mg/mL (144.06 mM) |
| | EOS-62353 Usage And Synthesis |
| Description | GDC-0575, also known as ARRY-575 and RG7741, is a potent and selective inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2?nM. Chk1 inhibitor GDC-0575 specifically binds to and inhibits Chk1; this may result in tumor cells bypassing Chk1-dependent cell cycle arrest in the S and G2/M phases, which permits the cells to undergo DNA repair prior to entry into mitosis. |
| | EOS-62353 Preparation Products And Raw materials |
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