| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:LP 44;4-[2-(Methylthio)phenyl]-N-(1,2,3,4-tetrahydro-1-naphthalenyl)-1-piperazinehexanaMidehydrochloride
CAS:824958-12-5
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:LP 44
CAS:824958-12-5
Purity:98% by HPLC Remarks:LP 44 is a 5-HT7 receptor agonist with Ki value of 0.22 nM that displays selectivity over 5-HT1A and 5-HT2A receptors (200- and > 1000-fold respectively). It induces relaxation of substance P-induced
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| Product Name: | LP 44 | | Synonyms: | LP 44;4-[2-(Methylthio)phenyl]-N-(1,2,3,4-tetrahydro-1-naphth alenyl)-1-piperazinehexanamide hydrochloride;LP44 (hydrochloride);4-[2-(Methylthio)phenyl]-N-(1,2,3,4-tetrahydro-1-naphthalenyl)-1-piperazinehexanamidehydrochlo;6-[4-(2-methylsulfanylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide:hydrochloride;compound 5 [PMID 17649988]. | | CAS: | 824958-12-5 | | MF: | C27H37N3OS.ClH | | MW: | 488.136 | | EINECS: | | | Product Categories: | | | Mol File: | 824958-12-5.mol |  |
| | LP 44 Chemical Properties |
| storage temp. | 2-8°C | | solubility | DMSO: >10mg/mL | | form | solid |
| | LP 44 Usage And Synthesis |
| Uses | LP 44 Hydrochloride is used in the preparation of (tetrahydronaphthalenyl)arylpiperazinealkylamides which an agonist of the serotonin 5-HT7 receptor. | | Biological Activity | High affinity 5-HT 7 receptor agonist (K i = 0.22 nM) that displays selectivity over 5-HT 1A and 5-HT 2A receptors (200- and > 1000-fold respectively). Induces relaxation of substance P-stimulated guinea pig ileum (EC 50 = 2.56 μ M). |
| | LP 44 Preparation Products And Raw materials |
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