|
|
| | vobasine Basic information |
| Product Name: | vobasine | | Synonyms: | vobasine;Vobasan-17-oic acid, 3-oxo-, methyl ester | | CAS: | 2134-83-0 | | MF: | C21H24N2O3 | | MW: | 352.43 | | EINECS: | | | Product Categories: | | | Mol File: | 2134-83-0.mol |  |
| | vobasine Chemical Properties |
| Melting point | 111-113 °C | | Boiling point | 526.8±50.0 °C(Predicted) | | density | 1?+-.0.06 g/cm3(Predicted) | | pka | 14.95±0.40(Predicted) |
| | vobasine Usage And Synthesis |
| Description | A further alkaloid occurring in Voacanga africana, the base forms cubic crystals from MeOH and is strongly laevorotatory with [α]23D- 158.5° (c 1.0, CHCI3) or
- 148.3° (c 1.0, MeOH). The ultraviolet spectrum has two absorption maxima at
239 and 315 mμ. The alkaloid forms a hydrochloride as prismatic plates from
MeOH, m.p. 245-8°C (dec.); [α]22D - 120.1° (c 1.0, MeOH); the methiodide,
m.p. 212-4°C (dec.); [α]23D - 117.2° (c 1.0, MeOH) and the 2:4-dinitrophenylhydrazone
as deep red crystals, m.p. 172-5°C. | | Definition | ChEBI: An indole alkaloid that is vobasan in which the bridgehead methyl group is substituted by a methoxycarbonyl group and an additional oxo substituent is present in the 3-position. | | References | Renner., Experientia, 15, 185 (1959)
Renner, Prins., ibid, 17,209 (1961)
Renneretal., Helv. Chim. Acta, 46,2186 (1963)
Cava et al., Tetrahedron Lett., 53 (1963)
Budzikiewicz et al., Bull. Soc. Chim. Fr., 1899 (1963) |
| | vobasine Preparation Products And Raw materials |
|