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Sigma-Aldrich
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Product Name:Thielavin B CAS:71950-67-9 Purity:>=95% (LC/MS-UV) Package:1MG Remarks:SMB00566-1MG
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| thielavin B Basic information |
Product Name: | thielavin B | Synonyms: | thielavin B;4-[(2,4-Dihydroxy-3,6-dimethylbenzoyl)oxy]-2-methoxy-3,5,6-trimethylbenzoic acid 4-carboxy-3-methoxy-2,5,6-trimethylphenyl ester | CAS: | 71950-67-9 | MF: | | MW: | 0 | EINECS: | | Product Categories: | | Mol File: | 71950-67-9.mol | |
| thielavin B Chemical Properties |
storage temp. | -20°C | solubility | DMF: soluble; DMSO: soluble; Ethanol: soluble | form | White to off-white powder. |
| thielavin B Usage And Synthesis |
Description | Thielavin B is a fungal metabolite that contains O-substituted salicylic acid. It inhibits cyclooxygenase, blocking both the conversion of arachidonic acid to Prostaglandin H2 (PGH2) and the conversion of PGH2 to PGE2 (, IC50s = 40 and 9 μM, respectively). Thielavin B also inhibits the reverse transcriptase of avian myeloblastosis virus, bacterial transglycosylases, and telomerase activity. | Uses | Thielavin B is a fungal metabolite of?Thielavia terricola that contains O-substituted salicylic acid. It is an inhibitor of viral reverse transcriptase and telomerase. | Uses | Thielavin B is a fungal metabolite closely related to thielavin A but reported to have a slightly different biochemical profile. Thielavins inhibit glucose-6-phosphatase. Thielavin B is a potent inhibitor of phospholipase C, and inhibits peptidoglycan formation and prostaglandin biosynthesis. | General Description | Natural product derived from fungal source. |
| thielavin B Preparation Products And Raw materials |
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