| Company Name: |
Suzhou Meishi Biotechnology Co., Ltd.
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| Tel: |
1173954148q |
| Email: |
meishipharma@126.com |
| Products Intro: |
Product Name:153420-96-3
CAS:153420-96-3
Purity:99% HPLC Package:1G;5G;10G;100G;1KG;
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| | Atibeprone Basic information |
| Product Name: | Atibeprone | | Synonyms: | Atibeprone;2H-1-Benzopyran-2-one, 3,4-dimethyl-7-[[5-(1-methylethyl)-1,3,4-thiadiazol-2-yl]methoxy]- | | CAS: | 153420-96-3 | | MF: | C17H18N2O3S | | MW: | 330.4 | | EINECS: | | | Product Categories: | | | Mol File: | 153420-96-3.mol |  |
| | Atibeprone Chemical Properties |
| | Atibeprone Usage And Synthesis |
| Originator | Atibeprone,BASF | | Manufacturing Process | 10 mmol of 7-methoxy-3,4-dimethylcoumarin were stirred with 10 mmol
(4.04 g) of Lawesson's reagent (2,4-bis(4-methoxyphenyl)-1,3-dithia-2,4-
diphosphetane 2,4-disulfide) in 20 ml of toluene at 90°C for 1-2.5 h. After
cooling, the solvent was distilled off, the residue was taken up in DMF, and
water was added. The precipitate was filtered off with suction and the crude
3,4-dimethyl-7-(2-isopropyl-1,3,4-thiadiazol-5-ylmethoxy)-2-thiocoumarin was
purified by recrystallization from methanol or by column chromatography
(silica gel, methylene chloride). Yield: 98%, melting point: 134-135°C. | | Therapeutic Function | Antidepressant |
| | Atibeprone Preparation Products And Raw materials |
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