| Company Name: |
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.
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| Tel: |
21-57721279 |
| Email: |
sales@shydchem.com.cn |
| Products Intro: |
Product Name:tert-butyl 4-((3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)methoxy)piperidine-1-carboxylate
CAS:857652-30-3
Purity:97% Package:1g,5g,10g,100g,1kg
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| Company Name: |
Haoyuan Chemexpress Co., Ltd.
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| Tel: |
021-58950125 |
| Email: |
info@chemexpress.com |
| Products Intro: |
Product Name:PSN632408
CAS:857652-30-3
Purity:>98% Package:860RMB/5mg
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| | PSN632408 Basic information |
| Product Name: | PSN632408 | | Synonyms: | PSN632408;PSN 632408; PSN-632408; PSN 632408; PSN-632408;tert-butyl 4-((3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)methoxy)piperidine-1-carboxylate;1-Piperidinecarboxylic acid, 4-[[3-(4-pyridinyl)-1,2,4-oxadiazol-5-yl]methoxy]-, 1,1-dimethylethyl ester;PSN632408,PSN-632408 | | CAS: | 857652-30-3 | | MF: | C18H24N4O4 | | MW: | 360.41 | | EINECS: | | | Product Categories: | | | Mol File: | 857652-30-3.mol |  |
| | PSN632408 Chemical Properties |
| Boiling point | 513.8±60.0 °C(Predicted) | | density | 1.25±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | crystalline solid | | pka | 0.79±0.10(Predicted) |
| | PSN632408 Usage And Synthesis |
| Biological Activity | psn632408 is a novel, selective and small-molecule agonist of human and mouse gpr119 with ec50 values of 5.6±0.99 μm and 7.9±0.7 μm, respectively [1].psn632408 has been reported to activate human and mouse gpr119 in a yeast fluorimetric assay with ec50 of 5.6±0.99 μm and 7.9±0.7 μm, respectively. in hek-osgpr116 cells, camp level was dose-dependently increased by psn632408 with an ec50 of 1.9±0.14 μm.. in vivo, psn632408 induced food intake reduction by using a rat feeding model and acute hypophagic effects in dose-dependence [1]. | | references | [1] overton ha1, babbs aj, doel sm, fyfe mc, gardner ls, griffin g, jackson hc, procter mj, rasamison cm, tang-christensen m, widdowson ps, williams gm, reynet c.deorphanization of a g protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents. cell metab. 2006 mar;3(3):167-75 |
| | PSN632408 Preparation Products And Raw materials |
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