|
|
| | 2,4,6-TRIBROMO-3,5-DIFLUOROPYRIDINE Basic information | | Synthesis |
| Product Name: | 2,4,6-TRIBROMO-3,5-DIFLUOROPYRIDINE | | Synonyms: | 3,5-DIFLUORO-2,4,6-TRIBROMOPYRIDINE;2,4,6-TRIBROMO-3,5-DIFLUOROPYRIDINE;2,4,6-TRIBROMO-3,5-DIFLUOROPYRIDINE 97%;Pyridine, 2,4,6-tribromo-3,5-difluoro-;2,4,6-Tribromodifluoro-pyridine | | CAS: | 30841-93-1 | | MF: | C5Br3F2N | | MW: | 351.77 | | EINECS: | | | Product Categories: | Pyridine | | Mol File: | 30841-93-1.mol |  |
| | 2,4,6-TRIBROMO-3,5-DIFLUOROPYRIDINE Chemical Properties |
| Melting point | 108-110°C | | Boiling point | 251.5±35.0 °C(Predicted) | | density | 2.519±0.06 g/cm3(Predicted) | | pka | -5.26±0.10(Predicted) | | CAS DataBase Reference | 30841-93-1(CAS DataBase Reference) |
| | 2,4,6-TRIBROMO-3,5-DIFLUOROPYRIDINE Usage And Synthesis |
| Synthesis | Combination of HBr and AlBr3 would be expected to give a super-acid
(H+ AIBq-) and we might anticipate that this would provide a very powerful brominating
agent. Indeed it has been shown that tetrafluoropyrazine (which is less basic than
pentafluoropyridine) gives tetrabromopyrazine on treatment with H+ AlBr4-, therefore,
we expected that H+ AIBq- would react well with (3). This proved to be the case and
reaction of pentafluoropyridine with H+ AIBq- gave 2,4,6-tribromo-3,5-difluoropyridine
as a single product in high yield.
|
| | 2,4,6-TRIBROMO-3,5-DIFLUOROPYRIDINE Preparation Products And Raw materials |
|