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| | TETRAGASTRIN Basic information |
| Product Name: | TETRAGASTRIN | | Synonyms: | (3S)-3-[[(1S)-1-carbamoyl-2-phenyl-ethyl]carbamoyl]-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-phenylmethoxycarbonylamino-propanoyl]amino]-4-methylsulfanyl-butanoyl]amino]propanoic acid;4-7-Cholecystokinin-7 (swine) (9CI);Alaninamide, L-tryptophyl-L-methionyl-L-aspartylphenyl- (7CI);Alaninamide, L-tryptophyl-L-methionyl-L-aspartylphenyl-, L- (8CI);Cholecystokinin C-terminal tetrapeptide;Cholecystokinin(36-39);L-Phenylalaninamide, L-tryptophyl-L-methionyl-L-a-aspartyl-;Cholecystokinin fragment 30-33 amide | | CAS: | 1947-37-1 | | MF: | C29H36N6O6S | | MW: | 596.7 | | EINECS: | | | Product Categories: | | | Mol File: | 1947-37-1.mol |  |
| | TETRAGASTRIN Chemical Properties |
| Melting point | 185-195 °C | | Boiling point | 1070.0±65.0 °C(Predicted) | | density | 1.348±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | pka | 4.19±0.10(Predicted) |
| WGK Germany | 3 | | Toxicity | dog,LD,intravenous,> 100mg/kg (100mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITINGGASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"BEHAVIORAL: EXCITEMENT,Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 121, 1969. |
| | TETRAGASTRIN Usage And Synthesis |
| Uses | Cholecystokinin Fragment 30-33 Amide can be used for inactivating the CCK8 antiserum. The product can also be used as an antigen utilized in absorption control for testing the specificity of antisera. | | Definition | ChEBI: Tetragastrin is a tetrapeptide composed of L-tryptophan, L-methione, L-aspartic acid and L-phenylalaninamide residues joined in sequence. It has a role as an anxiogenic and a human metabolite. It is a tetrapeptide and a peptidyl amide. | | Hazard | Moderately toxic by ingestion | | Biochem/physiol Actions | Cholecystokinin Fragment 30-33 Amide also referred to as CCK-4 or Trp-Met-Asp-Phe amide is a peptide fragment derived from peptide hormone cholecystokinin. CCK-4 is a panicogenic agent that induces panic attacks in humans. This property of the compound can be used in scientific research for testing the new anxiolytic drugs. |
| | TETRAGASTRIN Preparation Products And Raw materials |
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