藤黄内酯
| 中文名称 | 藤黄内酯 |
|---|---|
| 中文同义词 | (-)-羟基柠檬酸内酯;藤黄内酯;羟基柠檬酸内酯;藤黄内酯100MG 500MG;(2S,3S)-3-HYDROXY-5-OXOOXOLANE-2,3-DICARBOXYLIC ACI;羟基柠檬内酯 |
| 英文名称 | HYDROXYCITRIC ACID LACTONE, (-)-(P) |
| 英文同义词 | HYDROXYCITRIC ACID LACTONE, (-)-(P);(2S,3S)-3-Hydroxy-5-oxotetrahydrofuran-2,3-dicarboxylic acid;3-C-Carboxy-2-deoxy-D-erythropentaric acid 1,4-lactone;Garcinia lactone;(-)-Hydroxycitric acid lactone;(+)-Hydroxycitric acid lactone;D-erythro-Pentaric acid, 3-C-carboxy-2-deoxy-, 1,4-lactone;fat,synthesis,inhibit,agent,derivative,ATP Citrate Lyase,HIF,food,intake,Inhibitor,()Hydroxycitric acid lactone,weight-controlling,ACLY,( ) Hydroxycitric acid lactone |
| CAS号 | 27750-13-6 |
| 分子式 | C6H6O7 |
| 分子量 | 190.11 |
| EINECS号 | |
| 相关类别 | 标准品 |
| Mol文件 | 27750-13-6.mol |
| 结构式 |  |
藤黄内酯 性质
| 沸点 | 673.6±55.0 °C(Predicted) |
|---|---|
| 密度 | 1.976 |
| 溶解度 | DMSO：250 mg/mL（1315.03 mM；需要超声波） |
| 酸度系数(pKa) | 2.40±0.40(Predicted) |
(-)-Hydroxycitric acid lactone (Garcinia lactone) 是一种减肥药，也是一种很受欢迎的减肥食品补充剂。(-)-Hydroxycitric acid lactone 是一种有效的 ATP-柠檬酸裂解酶 抑制剂。(-)-Hydroxycitric acid lactone 催化柠檬酸盐线粒体外裂解为草酰乙酸和乙酰辅酶 A，限制了脂肪酸合成所需乙酰辅酶 A 单位的可用性。
(-)-Hydroxycitric acid lactone (1000-3000mg/kg; fed for a period of 4 weeks) significantly decreases body weight at 2000 and 3000 mg/kg in chicken.
| Animal Model: | 1-day-old male broiler chickens |
| Dosage: | 1000, 2000, 3000 mg/kg |
| Administration: | Fed for a period of 4 weeks |
| Result: | Body weight and average daily gain (ADG) in the 2000 mg/kg and 3000 mg/kg were significantly lower. |