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| | ALEXIDINE DIHYDROCHLORIDE Basic information |
| | ALEXIDINE DIHYDROCHLORIDE Chemical Properties |
| Melting point | 220-224 | | Boiling point | 574.5±60.0 °C(Predicted) | | density | 1.10±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Methanol (Slightly) | | form | Solid | | pka | 12.34±0.10(Predicted) | | color | White to Off-White |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | Hazard Note | Irritant | | HS Code | 29224995 |
| | ALEXIDINE DIHYDROCHLORIDE Usage And Synthesis |
| Chemical Properties | White Powder with Light Yellow Cast | | Originator | Alexidine ,Science Lab. | | Uses | Alexidine Dihydrochloride has antibacterial, antiplaque properties against Streptococcus mutans, Actinomyces ciscosus, and Actinomyces naesludii. | | Definition | ChEBI: An amphipathic bisbiguanide with a structure consisting of two (2-ethylhexyl)guanide units linked by a hexamethylene bridge. | | Manufacturing Process | A mixture of 16 g (0.09 mole) 1,1'-hexamethylene-bis(3-cyanoguanidine) and
20 d (0.12 mole) 2-ethylhexylamine hydrochloride is heated at 150-155°C for
3 hours. The mixture is cooled and the product is dissolved in 75 ml of hot
water. The solution is treated with activated charcoal. 1,1'-Hexamethylene-bis-
(5-(ethylhexyl)biguanide) is recrystalluized from methanol-ether, melting point
220.6-223.4°C. | | Therapeutic Function | Antiseptic |
| | ALEXIDINE DIHYDROCHLORIDE Preparation Products And Raw materials |
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