- Danofloxacin mesylate
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- $0.00 / 25kg
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2024-04-29
- CAS:119478-55-6
- Min. Order: 25kg
- Purity: 99.0%
- Supply Ability: 10tongs
- Danofloxacin Mesylate
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- $0.00 / 1kg
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2024-04-05
- CAS:119478-55-6
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1000kg
- Danofloxacin Mesylate
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- $0.00 / 1g
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2024-03-12
- CAS:119478-55-6
- Min. Order: 1g
- Purity: 98% HPLC
- Supply Ability: 100kg
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| Product Name: | Danofloxacin mesylate | | Synonyms: | 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-quinolin-3-carboxylic acid methanesulfonate (1:1);3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-, methanesulfonate (1:1);Mesylate Dan Nuosha star;DANOFLOXACIN MESILATE;DANOFLOXACIN MESULATE;DANOFLOXACIN MESYLATE;DANOFLOXANCIN MESYLATE;1-cyclopropyl-6-fluoro-7-[(1s,4s)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid monomethanesulfonate | | CAS: | 119478-55-6 | | MF: | C20H24FN3O6S | | MW: | 453.48 | | EINECS: | 638-813-3 | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 119478-55-6.mol |  |
| | Danofloxacin mesylate Chemical Properties |
| Melting point | 337-339°C | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | solubility | Aqueous Base (Slightly, Sonicated), DMSO (Slightly, Sonicated) | | form | Solid | | color | White to Off-White | | Stability: | Hygroscopic | | CAS DataBase Reference | 119478-55-6(CAS DataBase Reference) |
| Safety Statements | 24/25 | | HS Code | 29339900 |
| | Danofloxacin mesylate Usage And Synthesis |
| Description | Danofloxacin is a fluoroquinolone antibiotic and a type II topoisomerase inhibitor. It has a broad antimicrobial spectrum. It can be used as an anti-infective agent for veterinary use only.
| | Brand Name(s) in US | Advocin
| | Reference | J. A. Schrickx, J. Fink-Gremmels, Danofloxacin-mesylate is a substrate for ATP-dependent efflux transporters, British Journal of Pharmacology, 2009, vol. 150, pp. 463-469
| | Description | Danofloxacin is a fluoroquinolone antibiotic. In vitro, danofloxacin has activity against 68 field isolates of Mycoplasma species isolated from cattle, swine, and poultry with MICs ranging from 8 to 500 nM. It is protective in vivo against P. multocida, E. coli, and S. choleraesuis in mice with protective doses of 0.31, 0.40, and 2.42 mg/kg, respectively. Formulations containing danofloxacin are widely used to prevent infectious disease in livestock. | | Chemical Properties | Crystalline Solid | | Uses | Fluorinated quinolone antibacterial. | | Uses | Danofloxacin is a fluoroquinolone antibacterial for veterinary use, with MIC90 of 0.28 μM | | Definition | ChEBI: Danofloxacin mesylate is a member of quinolines. | | Veterinary Drugs and Treatments | Danofloxacin mesylate injection is indicated for the treatment of
Bovine Respiratory Disease (BRD) associated with Mannheimia
(Pasturella) hemolytica and P. multocida in cattle (not dairy or
veal). Because of the drug’s spectrum of activity, it may also be of
benefit in the treatment of infections caused by Histophilus somni
(Haemophilus somnus) or M. bovis, but the drug is not labeled (at
the time of writing) for treating these pathogens. In other countries,
danofloxacin may be labeled for use in swine and chickens
(non-laying), but in the USA it is illegal to use the drug in an extralabel
manner in food-producing species.
Danofloxacin may be of benefit in treating susceptible infections in
adult horses, camelids and other non-food producing species. |
| | Danofloxacin mesylate Preparation Products And Raw materials |
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