- LY 344864
-
- $1.00 / 1g
-
2019-12-25
- CAS:186544-26-3
- Min. Order: 1g
- Purity: 99.99%
- Supply Ability: 200kg
|
| | LY 344864 Basic information |
| Product Name: | LY 344864 | | Synonyms: | LY 344864;LY 344864 hydrochloride;N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamidehydrochloride;(R)-N-[3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide;(R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride;LY344864 HCL;LY344864;LY-344864;CS-660 | | CAS: | 186544-26-3 | | MF: | C21H22FN3O | | MW: | 351.42 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 186544-26-3.mol |  |
| | LY 344864 Chemical Properties |
| Boiling point | 471.9±45.0 °C(Predicted) | | density | 1.28±0.1 g/cm3(Predicted) | | storage temp. | Store at +4°C | | solubility | DMSO : ≥ 350 mg/mL (995.96 mM) | | pka | 14.12±0.40(Predicted) | | form | Powder |
| | LY 344864 Usage And Synthesis |
| Uses | LY-344864 Hydrochloride is used as a selective 5-HTIF receptor agonist. | | Biological Activity | Potent, selective 5-HT 1F receptor agonist (EC 50 = 3 nM). Displays > 80-fold selectivity over other 5-HT receptors (K i values are 0.006, 0.53, 0.55, 0.56, 1.42, 1.70, 3.50, 3.94 and 4.85 μ M for 5-HT 1F , 5-HT 1A , 5-HT 1B , 5-HT 1D , 5-HT 1E , 5-HT 2B , 5-HT 2C , 5-HT 2A and 5-HT 7 receptors respectively). Inhibits neurogenic dural inflammation in vivo following i.v. and oral administration. |
| | LY 344864 Preparation Products And Raw materials |
|