(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4- manufacturers
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| | (+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4- Basic information |
| Product Name: | (+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4- | | Synonyms: | (+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4-;4-Iodo-2,5-dimethoxyphenylisopropylamine, hydrochloride;Benzeneethanamine, 4-iodo-2,5-dimethoxy-alpha-methyl-, hydrochloride;Doi cpd hydrochloride;4-Iodo-2,5-dimethoxy-α-methylbenzeneethanaminehydrochloride;BenzeneethanaMine,4-iodo-2,5-diMethoxy-a-Methyl-, hydrochloride (1:1);(±)-2,5-Dimethoxy-4-Iodoamphetamine hydrochloride solution;DL-2,5-Dimethoxy-4-iodoamphetamine hydrochloride | | CAS: | 42203-78-1 | | MF: | C11H16INO2.ClH | | MW: | 357.613 | | EINECS: | 636-989-6 | | Product Categories: | | | Mol File: | 42203-78-1.mol |  |
| | (+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4- Chemical Properties |
| Fp | 9℃ | | storage temp. | Store at RT | | solubility | H2O: soluble10mg/mL | | form | solid | | color | white to off-white | | Water Solubility | Soluble to 50 mM in water |
| | (+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4- Usage And Synthesis |
| Uses | Hydrochloride (cas# 42203-78-1) is a useful research chemical.??DOI Hydrochloride is a 5-??HT2A??/2C agonist that stimulates hypothalamic neurons to increase the secretion of several hormones | | General Description | A Certified Spiking Solution? suited for GC/MS or LC/MS phenethylamine testing applications in forensic analysis, clinical toxicology, or urine drug testing. DOI is a D-substituted amphetamine in the phenethylamine family of hallucinogenic drugs. This designer drug is an extremely potent psychedelic with a long duration of action. | | Biological Activity | Brain penetrant, mixed 5-HT 2A /5-HT 2C receptor agonist (K i values are 0.7, 2.4 and 20 nM for 5-HT 2A , 5-HT 2C and 5-HT 2B receptors respectively). Reduces rapid eye movement (REM) and slow wave sleep and increases waking in the rat. Hallucinogenic agent. Acts via 5-HT 2A receptors to inhibit the inflammatory effects of tumor necrosis factor (TNF)- α . | | Biochem/physiol Actions | (±)-DOI hydrochloride is a potent and selective 5-HT2 serotonin receptor agonist that crosses the blood-brain barrier, increases dopamine turnover and the treatment with DOI counteracted the expression of the nicotine-induced locomotor and neurochemical sensitization, but had no effect on nicotine-induced behavioral disinhibition. The responses to DOI provide evidence that of these receptors are abundant in the cortex, and show relatively lower levels in hippocampus and cerebellum. | | storage | Store at RT |
| | (+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4- Preparation Products And Raw materials |
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