CHROMONE-3-CARBOXALDEHYDE manufacturers
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| | CHROMONE-3-CARBOXALDEHYDE Basic information |
| Product Name: | CHROMONE-3-CARBOXALDEHYDE | | Synonyms: | 4H-1-Benzopyran-3-carboxaldehyde, 4-oxo-;CHROMONE-3-CARBOXALDEHYDE;BUTTPARK 29\06-40;AURORA KA-4820;AKOS B022468;AKOS BBS-00006952;3-CHROMONECARBALDEHYDE;3-FORMYLCHROMONE | | CAS: | 17422-74-1 | | MF: | C10H6O3 | | MW: | 174.15 | | EINECS: | 241-451-5 | | Product Categories: | Chromones | | Mol File: | 17422-74-1.mol |  |
| | CHROMONE-3-CARBOXALDEHYDE Chemical Properties |
| Melting point | 151-153 °C (lit.) | | Boiling point | 245.11°C (rough estimate) | | density | 1.2135 (rough estimate) | | refractive index | 1.4500 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | form | Crystalline Powder | | color | Orange | | Sensitive | Air Sensitive | | BRN | 472849 | | CAS DataBase Reference | 17422-74-1(CAS DataBase Reference) |
| Hazard Codes | Xi | | Safety Statements | 24/25 | | WGK Germany | 3 | | Hazard Note | Irritant | | HS Code | 29329900 |
| | CHROMONE-3-CARBOXALDEHYDE Usage And Synthesis |
| Chemical Properties | orange crystalline powder | | Uses | 3-Formylchromone may be used in the following studies:
- Preparation of library of novel (E)-3-(2-arylcarbonyl-3-(arylamino)allyl)-4H-chromen-4-ones, by three-component domino reactions with (E)-3-(dimethylamino)-1-arylprop-2-en-1-ones and anilines under catalyst-free conditions.
- Facile and ecofriendly synthesis of new chromonyl chalcones.
- Synthesis of 3-(2-hydroxybenzoyl)quinolines and 7H-chromeno[3,2-c]quinolin-7-ones.
| | Synthesis Reference(s) | Tetrahedron Letters, 14, p. 1995, 1973 DOI: 10.1016/S0040-4039(01)96102-7 | | General Description | Electrospray ionization mass spectrometry (ESI-MS) of protonated 3-formylchromone (3-FC) shows loss of H2 as a major fragmentation route to yield a ketene cation, which on reaction with water forms a protonated carboxylic acid. The invivo salubrious effects of 3-FC against nitrosodiethylamine (NDEA) mediated early hepatocellular carcinogenesis has been investigated. Synthesis and characterization of 3-FC and its derivatives has been reported. |
| | CHROMONE-3-CARBOXALDEHYDE Preparation Products And Raw materials |
| Raw materials | Ethanol-->Phosphorus oxychloride-->N,N-Dimethylacetamide-->2'-Hydroxyacetophenone | | Preparation Products | 2-Hydroxybenzophenone-->CHROMONE-->6-HYDROXY-6,9,10,11-TETRAHYDRO-CHROMENO[4,3-B]QUINOLIN-8-ONE-->Hydrazinecarbothioamide, 2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]--->4H-1-Benzopyran-3-carboxaldehyde, 4-oxo-, 3-oxime-->Benzenesulfonic acid, 4-methyl-, 2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazide-->1,3-dimethyl-5-[(4-oxo-4H-chromen-3-yl)methylidene]-1,3-diazinane-2,4,6-trione |
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