伊加地平
| 中文名称 | 伊加地平 |
|---|---|
| 中文同义词 | 伊加地平;化合物 T15553 |
| 英文名称 | Iganidipine |
| 英文同义词 | Iganidipine;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2,2-dimethyl-3-[4-(2-propen-1-yl)-1-piperazinyl]propyl] 5-methyl ester |
| CAS号 | 119687-33-1 |
| 分子式 | C28H38N4O6 |
| 分子量 | 526.63 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 119687-33-1.mol |
| 结构式 |  |
伊加地平 性质
| 储存条件 | Store at -20°C |
|---|---|
| 溶解度 | 溶于二甲基亚砜 |
Iganidipine 是一种钙离子通道拮抗剂。
Ca 2+
Iganidipine (0.03% solution) significantly increases optic nerve head (ONH) tissue blood velocity (NB ONH ) by 8 to 10% in treated eyes after a single administration (p<0.05) or by 18 to 35% after 7-, 14-, or 21-day twicedaily administration in rabbits (p<0.05). In monkeys, 0.03% and 0.1% Iganidipine significantly increases NB ONH in treated eyes by 20 and 41% after 7-day (p<0.05) twice-daily administration, respectively.