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Quetiapine fumarate

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Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
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Products Intro: Product Name:Quetiapine fumarate
CAS:111974-72-2
Purity:99% Package:990/KG
Company Name: Wuhan Dahua Weiye Pharmaceutical Chemical Co., Ltd.  Gold
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Products Intro:Product Name:quetiapine fumarate
CAS:111974-72-2
Purity:99 Package:1KG
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Products Intro:Product Name:Quetiapine Hemifumarate
CAS:111974-72-2
Purity:99% Package:1g; 25g
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Products Intro:Product Name:Quetiapine HeMifuMarate
CAS:111974-72-2
Purity:98.0%(LC&T) Package:25G,5G
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Products Intro:Product Name:Quetiapine fuMarate
CAS:111974-72-2
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Quetiapine fumarate Basic information
Antipsychotics Chemical properties Uses
Product Name:Quetiapine fumarate
Synonyms:2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-ethanol,(2E)-2-butenedioate (2:1);Quetiapine fumarate solution;Quetiapine for system suitability;QuetiapineFamarate;Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-, (2E)-2-butenedioate (2:1);SEROQUEL;QUETIAPINE FUMARATE;QUETIAPINE HEMIFUMARATE
CAS:111974-72-2
MF:C46H54N6O8S2
MW:883.09
EINECS:
Product Categories:Pharmaceutical raw materials;bulk drug material;Inhibitors;Active Pharmaceutical Ingredients;Antipsychotic;Intermediates & Fine Chemicals;Pharmaceuticals;Quetiapine;API
Mol File:111974-72-2.mol
Quetiapine fumarate Structure
Quetiapine fumarate Chemical Properties
Melting point 174-176°C
Fp 9℃
storage temp. -20°C Freezer
solubility DMSO: >10mg/mL
color white to off-white
CAS DataBase Reference111974-72-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,N,T,F
Risk Statements 22-50/53-52/53-39/23/24/25-23/24/25-11
Safety Statements 60-61-45-36/37-16
RIDADR UN1230 - class 3 - PG 2 - Methanol, solution
MSDS Information
Quetiapine fumarate Usage And Synthesis
AntipsychoticsQuetiapine fumarate is an antipsychotic, successfully developed by the AstraZeneca United States, it interacts with a variety of neurotransmitter receptors, in the brain, it displays high degree affinity for serotonin (5-HT2) receptor, and it is greater than dopamine D1 and D2 dopamine receptor affinity in the brain. Quetiapine also has high affinity for histamine H1 receptor and adrenergic α1 receptors, and low affinity for α2 receptors, but it basically displays no affinity for cholinergic muscarinic receptors or benzodiazepine receptors . It shows positive results in antipsychotic activity assays such as conditioned avoidance reflex . In clinical, it is mainly used in treatment for adults with severe depression, acute manic episodes of bipolar disorder and schizophrenia of different types . It is not only effective for the positive symptoms of schizophrenia, but also having a certain effect for negative symptoms . It can also alleviate affective symptoms associated with schizophrenia, such as depression, anxiety symptoms and cognitive deficits.
The above information is edited by the chemicalbook of Tian Ye.
Chemical propertiesWhite crystalline powder.
UsesA non-classical antipsychotics.
Chemical PropertiesWhite Crystalline Solid
UsesUsed as an antipsychotic. Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties
Usesantihypertensive adrenergic receptor blocking agent with selective alpha1- and nonselective beta-adrenergic receptor blocking actions in a single substance.
Quetiapine fumarate Preparation Products And Raw materials
Tag:Quetiapine fumarate(111974-72-2) Related Product Information
Sodium 4-aminosalicylate dihydrate Risperidone 1,9-Pyrazoloanthrone ABT 737 Fumaric acid 1-[2-(2-hydroxyethoxy)ethyl]piperazine 2HCL (intermediate of quetiapine fumarate) 1-hydroxyethoxyethylpiperazine (intermediate of quetiapine fumarate) 1-[2-(2-hydroxyethoxy)ethyl]piperazine (intermediate of quetiapine fumarate) 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-ethanol N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine Quetiapine fumarate