- DMT-dT Phosphoramidite
-
- $0.00 / 1kg
-
2023-04-04
- CAS:98796-51-1
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 500kg per month
- dT CE Phosphoramidite
-
- $100.00 / 15kg
-
2023-03-22
- CAS:98796-51-1
- Min. Order: 0.009999999776482582kg
- Purity: 99%
- Supply Ability: 5tons
- DMT-dT-CE
-
- $0.00 / 100mg
-
2023-03-14
- CAS:98796-51-1
- Min. Order: 100mg
- Purity: ≥99%
- Supply Ability: 20tons
|
| | DMT-dT Phosphoramidite Basic information |
| Product Name: | DMT-dT Phosphoramidite | | Synonyms: | 5'-O-DMT-thymidine 3'-CE phosphoramidite;DMT-dT PhosphoraMidite;5'-O-[Bis(4-Methoxyphenyl)phenylMethyl]-thyMidine 3'-[2-cyanoethyl N,N-bis(1-Methylethyl)phosphoraMidite];5′-O-(4,4′-dimethoxytrityl)-2′-deoxythymidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite];5'-O-DMT-2'-deoxythymidine-3'-CE Phosphoramidite;5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-5-methyluridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite;5'-O-(4,4'-Dimethoxytrityl)-thymidine-3'-cyanoethyl Phosphoramidite;5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYTHYMIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE | | CAS: | 98796-51-1 | | MF: | C40H49N4O8P | | MW: | 744.81 | | EINECS: | 685-410-3 | | Product Categories: | Pharmaceutical;RNAi;DNA;Amidite | | Mol File: | 98796-51-1.mol |  |
| | DMT-dT Phosphoramidite Chemical Properties |
| density | 1.22 at 20℃ | | vapor pressure | 0-0Pa at 20-50℃ | | storage temp. | Sealed in dry,2-8°C | | solubility | soluble, clear | | form | powder or granules | | pka | 9.55±0.10(Predicted) | | color | white to off-white | | InChIKey | UNOTXUFIWPRZJX-DJKSPSSYNA-N | | SMILES | O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)C[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,38,r| | | LogP | 5.8 at 20℃ |
| WGK Germany | 3 | | HS Code | 29349990 |
| | DMT-dT Phosphoramidite Usage And Synthesis |
| Uses | 5''-O-[Bis(4-Methoxyphenyl)phenylmethyl]-thymidine 3''-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a nucleotide and reactant used in the solid-phase synthesis of phosphorothioate oligonucleotides, and in the synthesis of lipophilic 5''-phosphoramidate derivatives of DNA and RNA oligonucleotides. | | Chemical Properties |
5'-O-DMT-Thymidine-CE Phosphoramidite is also known as DMT-dT Phosphoramidite. The IUPAC Name of this compound is (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. It allows for the introduction of thymidine units into oligonucleotides. Also, it has been used in various applications, including the synthesis of natural and unnatural DNA and RNA strands.
|
| | DMT-dT Phosphoramidite Preparation Products And Raw materials |
|