| Company Name: |
Adamas Reagent, Ltd.
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| Tel: |
400-6009262 16621234537 |
| Email: |
zhangsn@titansci.com |
| Products Intro: |
Product Name:1-(3,4,5-Trihydroxyphenyl)-1-Nonanone
CAS:100079-26-3
Purity:98% Package:100mg
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| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:THPN
CAS:100079-26-3
Purity:>=98% (HPLC) Package:25MG Remarks:SML1548-25MG
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| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:THPN
CAS:100079-26-3
Purity:98% by HPLC Package:1G;10G;100G Remarks:THPN is a Nur77 agonist. It binds to Nur77 receptor, resulting in autophagy in melanoma cell lines.
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| Product Name: | THPN | | Synonyms: | 1-(3,4,5-Trihydroxyphenyl)-1-nonanone;THPN;1-Nonanone, 1-(3,4,5-trihydroxyphenyl)-;THPN >=98% (HPLC) | | CAS: | 100079-26-3 | | MF: | C15H22O4 | | MW: | 266.33 | | EINECS: | | | Product Categories: | | | Mol File: | 100079-26-3.mol |  |
| storage temp. | 2-8°C | | solubility | Soluble in DMSO | | form | powder | | color | white to beige |
| Uses | THPN is a Nur77 agonist. THPN binds Nur77 and promotes translocation of the receptor to the mitochondria resulting in autophagy in melanoma cell lines. | | General Description | THPN or 1-(3,4,5-Trihydroxyphenyl)nonan-1-one, is a derivative of cytosporone B. | | Biochem/physiol Actions | THPN is potent nuclear receptor TR3 (Nur77) antagonist that induces autophagic cell death in melanoma. Co-application of THPN with Akt2 inhibitors significantly represses tumor growth in xenograft mouse model. |
| | THPN Preparation Products And Raw materials |
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