Topotecan NEW

Topotecan is a water-soluble semi-synthetic camptothecin derivative. It is an inhibitor of topoisomerase I. It can damage DNA by inhibiting the reconnection of single stranded DNA strands. Its cytotoxic effect is on the cell division of cancer cells. Phase is a specific drug for S phase cell cycle. It is a two-compartment model in the body, quickly distributed to the liver, kidney and other parts of the Chemicalbook, a single 30-minute intravenous infusion of 1.5mg/m2, t1/2α is 4.1-8.1 minutes, and the plasma protein binding rate is 6.6%-21.3%. Can enter the cerebrospinal fluid. Most of it is excreted by the kidneys, a small part is excreted by bile, and 90% is excreted within 12 hours. Reduced clearance in patients with renal insufficiency.

Company Information

   Hebei Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise,  The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.

Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.

The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market.  Welcome domestic and foreign customers to negotiate.

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