Rosuvastatin
| Price | $14 |
| Package | 1kg |
| Min. Order: | 1kg |
| Supply Ability: | 1000kg |
| Update Time: | 2022-12-26 |
Product Details
| Product Name: Rosuvastatin | CAS No.: 287714-41-4 |
| EC-No.: 689-191-5 | Min. Order: 1kg |
| Purity: 99% | Supply Ability: 1000kg |
| Release date: 2022/12/26 |
whatsapp:+86 15630195572
Email: sales02@hbduling.cn
| Product Name: | Rosuvastatin |
| Synonyms: | 7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(methyl-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid;Rosuvastatin;Rosuvastatin Acid;ROSUVASTATIN-D3 SODIUM SALT;(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-MethylMethanesulfonaMido)-6-(propan-2-yl)pyriMidin-5-yl]-3,5-dihydroxyhept-6-enoic acid;(3R,5S,E)-7-(4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid;R-2: TERT-BUTYL-(+) 7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYLSULFONYLAMINO) PYRIMIDINE-5-YL]-(3R, 5S)-DIOXANE-(E)-6-HEPTENATE;Rosuvastatin Impurity 21 |
| CAS: | 287714-41-4 |
| MF: | C22H28FN3O6S |
| MW: | 481.54 |
| EINECS: | 689-191-5 |
| Product Categories: | Isotopically Labeled Pharmaceutical Reference Standard;API |
| Mol File: | 287714-41-4.mol |
| Description | Rosuvastatin is the most recent FDA-approved statin (doses 5–40 mg) for the treatment of dyslipidemia. Rosuvastatin, which has a structure similar to other synthetic statins, has a long halflife (20–24 hours) similar to atorvastatin and hydrophilicity comparable to pravastatin. Consequently, rosuvastatin is minimally metabolized and has no significant cytochrome P450 drug interactions. The efficacy of rosuvastatin is superior to that of other statins. Compared to atorvastatin, rosuvastatin provides approximately an 8% additional lowering of LDL-C on an equivalent dose level. This provides modestly more efficacy than a doubling of the dose of atorvastatin. Rosuvastatin also increases HDL-C slightly more than atorvastatin, especially at the highest doses. |
| Uses | Rosuvastatin Calcium is a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM. |
Company Profile Introduction
Hebei duling International Trade Co., Ltd. is located in Shijiazhuang, the pharmaceutical capital of China. Our company operates in various forms, including production, sales and overseas trade. At the same time, we can provide biotechnology development, consultation, exchange and promotion, technical research of biomass energy, agricultural scientific research and experimental development, etc. Our core sector is the R & D, production and sales of chemical additives and chemical intermediates.
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China- Since: 2020-09-17
- Address: Room 902, Unit 2, Building 8, Haolin Garden,Shangcheng,No. 69 Shangcheng Road, Xinhua District, Shij
INQUIRY
+86-17333973358
sales06@hbduling.cn