ChemicalBook >>Saccharin>>1,2-Benzisothiazol-3(2H)-one 1,1-dioxide(81-07-2)

1,2-Benzisothiazol-3(2H)-one 1,1-dioxide(81-07-2)

1,2-Benzisothiazol-3(2H)-one 1,1-dioxide(81-07-2)
Product IdentificationBack to Contents
【Product Name】

1,2-Benzisothiazol-3(2H)-one 1,1-dioxide
【Synonyms】

1,2-Benzisothiazol-3(2H)-one 1,1-dioxide
1,2-Dihydro-2-ketobenzisosulfonazole
Anhydro-o-sulfaminebenzoic acid
o-Benzoic sulfimide
Saccharin acid
Saccharinose
【CAS】

81-07-2
【Formula】

C7H5NO3S
【Molecular Weight】

183.19
【EINECS】

201-321-0
【RTECS】

DE4200000
【RTECS Class】

Tumorigen; Mutagen; Reproductive Effector
【Merck】

12,8463
【Beilstein/Gmelin】

6888
【Beilstein Reference】

4-2700-02649
Physical and Chemical PropertiesBack to Contents
【Appearance】

White crystals. Odorless or faintly aromatic odor. Sweet taste.
【Solubility in water】

3.3 g/L
【Melting Point】

225 - 227
【Boiling Point】

sublimes
【Density】

0.828 g/cm3 (20 C)
【pKa/pKb】

1.31 (pKa)
【Partition Coefficient】

.91
【Usage】

Non-caloric synthetic sweetener.
【Refractive Index】

1.5878 (20 C)
First Aid MeasuresBack to Contents
【Ingestion】

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Wash mouth out with water. Get medical aid if irritation or symptoms occur.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
【Skin】

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Handling and StorageBack to Contents
【Storage】

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
【Handling】

Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Hazards IdentificationBack to Contents
【Inhalation】

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
【Skin】

May cause skin irritation.
【Eyes】

May cause eye irritation.
【Ingestion】

May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】

May cause cancer according to animal studies. May cause reproductive and fetal effects. Laboratory experiments have resulted in mutagenic effects.
【Exposure limit(s)】

OSHA: Possible Select carcinogen.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
【Fire Potential】

This material is probably combustible.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Stability and ReactivityBack to Contents
【Stability】

Stable under normal temperatures and pressures.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Carbon monoxide, oxides of nitrogen, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide.
Transport InformationBack to Contents
【HS Code】

2925 11 00
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