ChemicalBook >>Chenodeoxycholic acid>>3alpha,7alpha-Dihydroxy-5beta-cholanic acid(474-25-9)

3alpha,7alpha-Dihydroxy-5beta-cholanic acid(474-25-9)

3alpha,7alpha-Dihydroxy-5beta-cholanic acid(474-25-9)
Product IdentificationBack to Contents
【Product Name】

3alpha,7alpha-Dihydroxy-5beta-cholanic acid
【Synonyms】

17b-(1-Methyl-3-carboxypropyl)etiocholane-3a,7a-diol
3a,7a-Dihydroxy-5b-cholanoic acid
7a-Hydroxylithocholic acid
Anthropodesoxycholic acid
Chenodesoxycholic acid
Cholan-24-oic acid, 3,7-dihydroxy-, (3a,5b,7a)-
【CAS】

474-25-9
【Formula】

C24H40O4
【Molecular Weight】

392.57
【EINECS】

207-481-8
【RTECS】

FZ1980000
【RTECS Class】

Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data
【Merck】

12,2096
【Beilstein/Gmelin】

3219887
【Beilstein Reference】

4-10-00-01604
Physical and Chemical PropertiesBack to Contents
【Appearance】

White solid.
【Solubility in water】

Insoluble
【Melting Point】

164.85 - 165.85
【Density】

1.162 g/cm3
【pKa/pKb】

4.76 (pKa)
【Usage】

Bile acid. A detrrgent used to solubilize fats. Used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.
First Aid MeasuresBack to Contents
【Ingestion】

Get medical aid. Wash mouth out with water.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Handling and StorageBack to Contents
【Storage】

Store in a cool, dry place. Store in a tightly closed container.
【Handling】

Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Use only in a chemical fume hood.
Hazards IdentificationBack to Contents
【Inhalation】

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
【Skin】

May cause skin irritation.
【Eyes】

May cause eye irritation.
【Ingestion】

The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Exposure Effects】

Chronic ingestion may cause liver damage. Prolonged or repeated exposure may cause adverse reproductive effects.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Vacuum or sweep up material and place into a suitable disposal container.
Stability and ReactivityBack to Contents
【Stability】

No data.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Carbon monoxide, carbon dioxide.
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