ChemicalBook >>(R)-Phenylephrine Hydrochlorid>>(R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride(61-76-7)

(R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride(61-76-7)

(R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride(61-76-7)
Product IdentificationBack to Contents
【Product Name】

(R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride
【Synonyms】

Benzenemethanol, 3-hydroxy-a-[(methylamino)methyl]-, hydrochloride, (aR)-
Isophrin hydrochloride
l-m-Hydroxy-a-[(methylamino)methyl]benzyl alcohol hydrochloride
meta-Synephrine hydrochloride
neo-Synephrine hydrochloride
R-(-)-m-Synephrine hydrochloride
【CAS】

61-76-7
【Formula】

C9H14ClNO2
【Molecular Weight】

203.67
【EINECS】

200-517-3
【RTECS】

DO7525000
【RTECS Class】

Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data
【Merck】

12,7440
【Beilstein/Gmelin】

4158948
【Beilstein Reference】

3-13-00-02236
Physical and Chemical PropertiesBack to Contents
【Appearance】

Odorless white microcrystalline powder. Bitter taste.
【Melting Point】

138 - 141
【pKa/pKb】

pK1 8.77; pK2 9.84(at 25℃) (pKa)
【Usage】

Adrenergic drug.
First Aid MeasuresBack to Contents
【Ingestion】

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and StorageBack to Contents
【Storage】

Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
【Handling】

Wash thoroughly after handling. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Hazards IdentificationBack to Contents
【Ingestion】

Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea.
【Inhalation】

May cause respiratory tract irritation.
【Skin】

May cause skin irritation.
【Eyes】

May cause eye irritation.
【Hazards】

Contact with metals may evolve flammable hydrogen gas.
【EC Risk Phrase】

R 22 36/37/38
【EC Safety Phrase】

S 26 36/37/39
【UN (DOT)】

1760
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Fire Fighting MeasuresBack to Contents
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
【Fire Potential】

This material is probably combustible.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability and ReactivityBack to Contents
【Incompatibilities】

Oxidizing agents, acids, acid chlorides, acid anhydrides.
【Stability】

Stable under normal temperatures and pressures.
【Decomposition】

Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.
【Combustion Products】

Fire may produce irritating, corrosive and/or toxic gases.
Transport InformationBack to Contents
【UN Number】

1760
【Hazard Class】

8
【Packing Group】

I; II; III
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