ARQ-621

价格	￥500	￥1000	￥2000
包装	10mg	50mg	1000mg

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ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.
体外活性	ARQ 621 demonstrates anti-tumor activity against a wide range of human cancer cell lines in vitro, including colon, lung, endometrial, bladder, and hematologic cancer cell lines, with significantly less cytotoxicity against hematopoietic cells.
体内活性	ARQ 621, as a novel clinical stage drug candidate, inhibits a number of xenografts grown in athymic mice, such as pancreatic, breast, prostate, and ovarian carcinomas with no hematological changes. Furthermore, for ARQ 621, there is no envidence of bone marrow toxicity in pre-clinical mouse efficacy models or safety studies in rats and dogs.

关键字： ARQ-621;1095253-39-6;

长江化学有限公司位于天津市滨海新区。本公司可提供各种分子砌块，医药中间体，有机合成试剂的销售以及定制服务，有机合成FTE服务，快速HNMR、LCMS、HPLC检测服务，是集研发、销售和服务为一体的创新药物综合服务平台

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