N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine
![N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine price.](/CAS/GIF/1097917-15-1.gif)
|
- $39 - $12210
- Product name: N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine
- CAS: 1097917-15-1
- MF: C29H40N8O3S
- MW: 580.74
- EINECS:200-258-5
- MDL Number:MFCD21609265
- Synonyms:ASP3026;ASP 3026;ASP-3026;N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfon;ASP 3026;N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine;1,3,5-Triazine-2,4-diamine, N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-;N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine ASP 3026;ASP 3026; ASP-3026;CS-286
28 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Tocris
- TRC
- Usbiological
Package
- 50
- 1MG
- 5MG
- 10
- 10mg
- 25mg
- 50MG
- 100mg
- 250mg
- 1000mg
- 1g
- 5g
- ManufacturerAK Scientific
- Product numberSYN5648
- Product descriptionASP3026
- Packaging10mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001435
- Product descriptionASP-3026 95.00%
- Packaging1MG
- Price$480
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001435
- Product descriptionASP-3026 95.00%
- Packaging5MG
- Price$786.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001435
- Product descriptionASP-3026 95.00%
- Packaging10MG
- Price$866.25
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001435
- Product descriptionASP-3026 95.00%
- Packaging50MG
- Price$1374.45
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3193
- Product descriptionASP3026
- Packaging50mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2005
- Product descriptionASP3026 99%
- Packaging5mg
- Price$121
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181196
- Product descriptionASP3026 >98%
- Packaging100mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181196
- Product descriptionASP3026 >98%
- Packaging250mg
- Price$1208.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181196
- Product descriptionASP3026 >98%
- Packaging1000mg
- Price$2395.3
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18491
- Product descriptionASP3026 ≥98%
- Packaging1mg
- Price$39
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18491
- Product descriptionASP3026 ≥98%
- Packaging5mg
- Price$96
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18491
- Product descriptionASP3026 ≥98%
- Packaging10mg
- Price$152
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18491
- Product descriptionASP3026 ≥98%
- Packaging25mg
- Price$331
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0787
- Product descriptionASP3026 99.90%
- Packaging50mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0787
- Product descriptionASP3026 99.90%
- Packaging100mg
- Price$400
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5648 | ASP3026 | 10mg | $160 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001435 | ASP-3026 95.00% | 1MG | $480 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001435 | ASP-3026 95.00% | 5MG | $786.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001435 | ASP-3026 95.00% | 10MG | $866.25 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001435 | ASP-3026 95.00% | 50MG | $1374.45 | 2021-12-16 | Buy |
| ApexBio Technology | A3193 | ASP3026 | 50mg | $300 | 2021-12-16 | Buy |
| Axon Medchem | Axon2005 | ASP3026 99% | 5mg | $121 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181196 | ASP3026 >98% | 100mg | $615.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181196 | ASP3026 >98% | 250mg | $1208.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181196 | ASP3026 >98% | 1000mg | $2395.3 | 2021-12-16 | Buy |
| Cayman Chemical | 18491 | ASP3026 ≥98% | 1mg | $39 | 2024-03-01 | Buy |
| Cayman Chemical | 18491 | ASP3026 ≥98% | 5mg | $96 | 2024-03-01 | Buy |
| Cayman Chemical | 18491 | ASP3026 ≥98% | 10mg | $152 | 2024-03-01 | Buy |
| Cayman Chemical | 18491 | ASP3026 ≥98% | 25mg | $331 | 2024-03-01 | Buy |
| ChemScene | CS-0787 | ASP3026 99.90% | 50mg | $240 | 2021-12-16 | Buy |
| ChemScene | CS-0787 | ASP3026 99.90% | 100mg | $400 | 2021-12-16 | Buy |
Properties
Boiling point :794.3±70.0 °C(Predicted)
Density :1.276
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥14.53 mg/mL in DMSO; ≥4.9 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :8.14±0.42(Predicted)
Density :1.276
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥14.53 mg/mL in DMSO; ≥4.9 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :8.14±0.42(Predicted)
Safety Information
| Symbol(GHS): |
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
ASP3026 is an ATP-competitive, second-generation ALK inhibitor (IC50 = 3.5 nM) that also inhibits ROS (IC50 = 8.9 nM) and ACK (IC50 = 5.8 nM). It inhibits neuroblastoma-activating ALK mutants F1174L (IC50 = 10 nM) and R1275Q (IC50 = 5.4 nM) and demonstrates antitumor activity in xenograft mouse models. ASP3026 has been shown to overcome crizotinib resistance in non-small cell lung cancer, and is currently being evaluated in clinical trials of patients with ALK-positive solid tumors.More related product prices
PF-06463922 Crizotinib AP26113 ALK/IGF1R inhibitor 1256580-46-7 Ceritinib (LDK378) ABX-1431 936091-14-4 ASP-2215 SGI 7079 XL 228 UNC 0631 AGI6780Related product price
- PF-06463922
$37-1335 - Crizotinib
$5-1963.5 - AP26113
$28-1169
Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
CONIER CHEM AND PHARMA LIMITED
TargetMol Chemicals Inc.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
ShenZhen Trendseen Biological Technology Co.,Ltd.
Henan Fengda Chemical Co., Ltd
![N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine](https://img.chemicalbook.com/ProductImageEN/2019-12/small/14b936d0-093b-4cf8-8442-2e050c2f0f67.png){kind=small}