4SC-202
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- $84 - $2691.1
- Product name: 4SC-202
- CAS: 1186222-89-8
- MF: C30H29N5O6S2
- MW: 619.71116
- EINECS:
- MDL Number:MFCD25976779
- Synonyms:4SC-202;4SC-202 2-Propenamide, N-(2-aminophenyl)-3-[1-[[4-(1-methyl-1H-pyrazol-4-yl)phenyl]sulfonyl]-1H-pyrrol-3-yl]-, (2E)-, 4-methylbenzenesul;(E)-N-(2-aminophenyl)-3-(1-((4-(1-methyl-1H-pyrazol-4-yl)phenyl)sulfonyl)-1H-pyrrol-3-yl)acrylamide 4-methylbenzenesulfonate;4SC-202 tosylate;CS-1272;Domatinostat tosylate;4SC-202;4SC202;4SC 202;Domatinostat tosylate,Domatinostat,Apoptosis,inhibit,Histone deacetylases,Inhibitor,HDAC
23 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 1000mg
- ManufacturerAK Scientific
- Product number2836DF
- Product description4SC-202
- Packaging25mg
- Price$721
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4106
- Product description4SC-202
- Packaging5mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4106
- Product description4SC-202
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4106
- Product description4SC-202
- Packaging50mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4106
- Product description4SC-202
- Packaging100mg
- Price$700
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181409
- Product description4SC-202 >98%
- Packaging100mg
- Price$912.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181409
- Product description4SC-202 >98%
- Packaging250mg
- Price$1504.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181409
- Product description4SC-202 >98%
- Packaging1000mg
- Price$2691.1
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number26175
- Product description4SC-202
- Packaging5mg
- Price$141
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number26175
- Product description4SC-202
- Packaging10mg
- Price$253
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number26175
- Product description4SC-202
- Packaging25mg
- Price$558
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number26175
- Product description4SC-202
- Packaging50mg
- Price$979
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-3102
- Product descriptionDomatinostattosylate 99.66%
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3102
- Product descriptionDomatinostattosylate 99.66%
- Packaging10mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3102
- Product descriptionDomatinostattosylate 99.66%
- Packaging50mg
- Price$540
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3102
- Product descriptionDomatinostattosylate 99.66%
- Packaging100mg
- Price$1020
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2836DF | 4SC-202 | 25mg | $721 | 2021-12-16 | Buy |
| ApexBio Technology | B4106 | 4SC-202 | 5mg | $100 | 2021-12-16 | Buy |
| ApexBio Technology | B4106 | 4SC-202 | 10mg | $150 | 2021-12-16 | Buy |
| ApexBio Technology | B4106 | 4SC-202 | 50mg | $450 | 2021-12-16 | Buy |
| ApexBio Technology | B4106 | 4SC-202 | 100mg | $700 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181409 | 4SC-202 >98% | 100mg | $912.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181409 | 4SC-202 >98% | 250mg | $1504.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181409 | 4SC-202 >98% | 1000mg | $2691.1 | 2021-12-16 | Buy |
| Cayman Chemical | 26175 | 4SC-202 | 5mg | $141 | 2024-03-01 | Buy |
| Cayman Chemical | 26175 | 4SC-202 | 10mg | $253 | 2024-03-01 | Buy |
| Cayman Chemical | 26175 | 4SC-202 | 25mg | $558 | 2024-03-01 | Buy |
| Cayman Chemical | 26175 | 4SC-202 | 50mg | $979 | 2024-03-01 | Buy |
| ChemScene | CS-3102 | Domatinostattosylate 99.66% | 5mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-3102 | Domatinostattosylate 99.66% | 10mg | $180 | 2021-12-16 | Buy |
| ChemScene | CS-3102 | Domatinostattosylate 99.66% | 50mg | $540 | 2021-12-16 | Buy |
| ChemScene | CS-3102 | Domatinostattosylate 99.66% | 100mg | $1020 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥2.4 mg/mL in EtOH with gentle warming and ultrasonic; ≥62 mg/mL in DMSO
form :Powder
solubility :insoluble in H2O; ≥2.4 mg/mL in EtOH with gentle warming and ultrasonic; ≥62 mg/mL in DMSO
form :Powder
Safety Information
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Description
4SC-202 is an inhibitor of the class I histone deacetylases (HDACs) HDAC1-3 and the histone demethylase KDM1A. It reduces cell viability in a panel of colorectal cancer (CRC) cell lines when used at concentrations ranging from 1 to 10 μM and in patient-derived CRC cell lines when used at a concentration of 5 μM. 4SC-202 (5 μM) induces cell cycle arrest at the G2/M phase in HT-29 cells and primary human CRC cells and increases apoptosis in HT-29 cells in a concentration-dependent manner, an effect that is enhanced by the Akt inhibitors perifosine and MK-2206 . 4SC-202 (100 mg/kg, p.o., every other day) reduces tumor growth in an HT-29 mouse xenograft model when administered alone and to an enhanced degree when co-administered with oxaliplatin (Item No. 13106).Suppliers and manufacturers
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