BroMosporine
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- $37 - $2395.3
- Product name: BroMosporine
- CAS: 1619994-69-2
- MF: C17H20N6O4S
- MW: 404.44
- EINECS:-0
- MDL Number:MFCD26142669
- Synonyms:BroMosporine;ethyl 3-Methyl-6-(4-Methyl-3-(MethylsulfonaMido)phenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-ylcarbaMate;N-[6-(3-Methanesulfonamido-4-methylphenyl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]carbamate;CS-921;Carbamic acid, N-[3-methyl-6-[4-methyl-3-[(methylsulfonyl)amino]phenyl]-1,2,4-triazolo[4,3-b]pyridazin-8-yl]-, ethyl ester;BroMosporine USP/EP/BP;11,Bromosporine,inhibit,AML,colorectal cancer,CDK,antitumor,T cells,HCT116,Apoptosis,HT29,anticancer,Epigenetic Reader Domain,Inhibitor,Cyclin dependent kinase;KASUMI-1,HIV,AIDS,Human immunodeficiency virus,MV4
24 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Biorbyt Ltd
- BroadPharm
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Tocris
- TRC
Package
- 10
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1000mg
- 1g
- ManufacturerAK Scientific
- Product number2286AH
- Product descriptionBromosporine
- Packaging1mg
- Price$123
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA104099
- Product descriptionBromosporine 98+%
- Packaging5mg
- Price$191
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA104099
- Product descriptionBromosporine 98+%
- Packaging10mg
- Price$324
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA104099
- Product descriptionBromosporine 98+%
- Packaging50mg
- Price$826
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4186
- Product descriptionBromosporine
- Packaging5mg
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4186
- Product descriptionBromosporine
- Packaging10mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4186
- Product descriptionBromosporine
- Packaging50mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181360
- Product descriptionBromosporine >98%
- Packaging100mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181360
- Product descriptionBromosporine >98%
- Packaging250mg
- Price$1208.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181360
- Product descriptionBromosporine >98%
- Packaging1000mg
- Price$2395.3
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-25350
- Product descriptionBromosporine
- Packaging25mg
- Price$460
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14119
- Product descriptionBromosporine ≥98%
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14119
- Product descriptionBromosporine ≥98%
- Packaging5mg
- Price$108
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14119
- Product descriptionBromosporine ≥98%
- Packaging10mg
- Price$195
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14119
- Product descriptionBromosporine ≥98%
- Packaging25mg
- Price$353
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-3240
- Product descriptionBromosporine 99.60%
- Packaging5mg
- Price$115
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2286AH | Bromosporine | 1mg | $123 | 2021-12-16 | Buy |
| Ambeed | A104099 | Bromosporine 98+% | 5mg | $191 | 2021-12-16 | Buy |
| Ambeed | A104099 | Bromosporine 98+% | 10mg | $324 | 2021-12-16 | Buy |
| Ambeed | A104099 | Bromosporine 98+% | 50mg | $826 | 2021-12-16 | Buy |
| ApexBio Technology | A4186 | Bromosporine | 5mg | $99 | 2021-12-16 | Buy |
| ApexBio Technology | A4186 | Bromosporine | 10mg | $175 | 2021-12-16 | Buy |
| ApexBio Technology | A4186 | Bromosporine | 50mg | $550 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181360 | Bromosporine >98% | 100mg | $615.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181360 | Bromosporine >98% | 250mg | $1208.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181360 | Bromosporine >98% | 1000mg | $2395.3 | 2021-12-16 | Buy |
| BroadPharm | BP-25350 | Bromosporine | 25mg | $460 | 2021-12-16 | Buy |
| Cayman Chemical | 14119 | Bromosporine ≥98% | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 14119 | Bromosporine ≥98% | 5mg | $108 | 2024-03-01 | Buy |
| Cayman Chemical | 14119 | Bromosporine ≥98% | 10mg | $195 | 2024-03-01 | Buy |
| Cayman Chemical | 14119 | Bromosporine ≥98% | 25mg | $353 | 2024-03-01 | Buy |
| ChemScene | CS-3240 | Bromosporine 99.60% | 5mg | $115 | 2021-12-16 | Buy |
Properties
Density :1.46±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 25 mg/ml)
form :solid
pka :6.21±0.46(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 25 mg/ml)
form :solid
pka :6.21±0.46(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
Bromodomains play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction, by controlling the assembly of histone acetylation-dependent chromatin complexes. They serve as “readers” of histone acetylation marks, regulating the transcription of target promoters. For example, the cAMP response element-binding protein binding protein (CREBBP) bromodomain has been shown to modulate the stability and function of the tumor suppressor protein p53. Bromosporine is a non-selective bromodomain inhibitor. At 1 μM, it has been shown to accelerate fluorescence recovery after photobleaching (FRAP) recovery of BRD4 and CREBBP bromodomains in HeLa cells. This compound may be used in determining the biological roles of reader domains as well as a tool for the validation of functional assays. See the Structural Genomics Consortium (SGC) website for more information.More related product prices
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