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ChemicalBook >> CAS DataBase List >> GW 3965 HYDROCHLORIDE

GW 3965 HYDROCHLORIDE

GW 3965 HYDROCHLORIDE price.
  • $39 - $1700
  • Product name: GW 3965 HYDROCHLORIDE
  • CAS: 405911-17-3
  • MF: C33H31ClF3NO3.HCl
  • MW: 0
  • EINECS:
  • MDL Number:MFCD08276920
  • Synonyms:3-[3-[n-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride;3-[3-[n-(2-chloro-3-trifluoroMethylbenzyl)-(2,2-di…;GW3965 HCl;2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy]phenyl]acetic acid hydrochloride;GW3965 hydrochloride, >=98%;Benzeneacetic acid, 3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-, hydrochloride;GW3965 HCl Salt;3-[3-[[[2-Chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]benzeneacetic acid hydrochloride
27 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberX7584
  • Product descriptionGW3965HCl
  • Packaging10mg
  • Price$58
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5407
  • Product descriptionGW3965 hydrochloride
  • Packaging50mg
  • Price$547
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008828
  • Product descriptionGW-3965 HYDROCHLORIDE 95.00%
  • Packaging10MG
  • Price$262.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008828
  • Product descriptionGW-3965 HYDROCHLORIDE 95.00%
  • Packaging25MG
  • Price$1045.39
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8444
  • Product descriptionGW3965HCl
  • Packaging5mg
  • Price$69
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8444
  • Product descriptionGW3965HCl
  • Packaging10mg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60337
  • Product descriptionGW3965HCl ≥98%
  • Packaging10mg
  • Price$238
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC43370
  • Product description2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)acetic acid hydrochloride
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC43370
  • Product description2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)acetic acid hydrochloride
  • Packaging25mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC43370
  • Product description2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)acetic acid hydrochloride
  • Packaging50mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC43370
  • Product description2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)acetic acid hydrochloride
  • Packaging100mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC43370
  • Product description2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)acetic acid hydrochloride
  • Packaging250mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10054
  • Product descriptionGW 3965 (hydrochloride) ≥98%
  • Packaging1mg
  • Price$39
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10054
  • Product descriptionGW 3965 (hydrochloride) ≥98%
  • Packaging5mg
  • Price$97
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10054
  • Product descriptionGW 3965 (hydrochloride) ≥98%
  • Packaging10mg
  • Price$175
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0843
  • Product descriptionGW3965 hydrochloride 99.73%
  • Packaging5mg
  • Price$72
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X7584 GW3965HCl 10mg $58 2021-12-16 Buy
AK Scientific SYN5407 GW3965 hydrochloride 50mg $547 2021-12-16 Buy
American Custom Chemicals Corporation API0008828 GW-3965 HYDROCHLORIDE 95.00% 10MG $262.5 2021-12-16 Buy
American Custom Chemicals Corporation API0008828 GW-3965 HYDROCHLORIDE 95.00% 25MG $1045.39 2021-12-16 Buy
ApexBio Technology A8444 GW3965HCl 5mg $69 2021-12-16 Buy
ApexBio Technology A8444 GW3965HCl 10mg $105 2021-12-16 Buy
Arctom CFN60337 GW3965HCl ≥98% 10mg $238 2021-12-16 Buy
Biosynth Carbosynth FC43370 2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)acetic acid hydrochloride 10mg $50 2021-12-16 Buy
Biosynth Carbosynth FC43370 2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)acetic acid hydrochloride 25mg $100 2021-12-16 Buy
Biosynth Carbosynth FC43370 2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)acetic acid hydrochloride 50mg $180 2021-12-16 Buy
Biosynth Carbosynth FC43370 2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)acetic acid hydrochloride 100mg $300 2021-12-16 Buy
Biosynth Carbosynth FC43370 2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)acetic acid hydrochloride 250mg $500 2021-12-16 Buy
Cayman Chemical 10054 GW 3965 (hydrochloride) ≥98% 1mg $39 2024-03-01 Buy
Cayman Chemical 10054 GW 3965 (hydrochloride) ≥98% 5mg $97 2024-03-01 Buy
Cayman Chemical 10054 GW 3965 (hydrochloride) ≥98% 10mg $175 2024-03-01 Buy
ChemScene CS-0843 GW3965 hydrochloride 99.73% 5mg $72 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMSO: ≥20mg/mL
form :powder
color :white
InChIKey :NMPUWJFHNOUNQU-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The liver X receptors, LXRα and LXRβ, are nuclear receptors that act as ligand-dependent transcription factors. They modulate cholesterol, fatty acids, and glucose homeostasis. GW 3965 is an orally-active agonist of LXRα and LXRβ, activating the human isoforms with EC50 values of 190 and 30 nM, respectively. It alters LXR-regulated gene expression in mice and rats, affecting pathways related to glucose and lipid metabolism. GW 3965 also affects inflammation and pressor responses through LXRα and LXRβ.

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