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ChemicalBook >> CAS DataBase List >> Ketoconazole

Ketoconazole

Ketoconazole price.
  • $7 - $1674.75
  • Product name: Ketoconazole
  • CAS: 65277-42-1
  • MF: C26H28Cl2N4O4
  • MW: 531.43
  • EINECS:265-667-4
  • MDL Number:MFCD00058579
  • Synonyms:,3-dioxolan-4-yl)methoxy)phenyl)-,cis- ;fungarest ;fungoral ;ketoderm ;ketoisdin ;kw-1414 ;orifungalm ;panfungol
58 prices
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  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Atlantic Research Chemicals
  • AvaChem
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • ChemScene
  • Crysdot
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
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  • 10mM(in 1mL DMSO)
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  • 1ml
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  • 1gm:
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-K0016-G001
  • Product descriptionKetoconazole 99.0-101.0%(EP,Titration)
  • Packaging1g
  • Price$71
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1211
  • Product descriptionKetocanazole 98%
  • Packaging250g
  • Price$620
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberF963
  • Product descriptionKetoconazole
  • Packaging1g
  • Price$21
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ94064
  • Product descriptionKetoconazole
  • Packaging10g
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ94064
  • Product descriptionKetoconazole
  • Packaging25g
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67352
  • Product descriptionKetoconazole, 2 mg/ml in methanol, sterile-filtered
  • Packaging1ml
  • Price$47.9
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67352
  • Product descriptionKetoconazole, 2 mg/ml in methanol, sterile-filtered
  • Packaging5x1ml
  • Price$150
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63367
  • Product descriptionKetoconazole, 98%
  • Packaging5g
  • Price$212
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63367
  • Product descriptionKetoconazole, 98%
  • Packaging25g
  • Price$698.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA183059
  • Product descriptioncis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine 98+%
  • Packaging1g
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA183059
  • Product descriptioncis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine 98+%
  • Packaging5g
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA183059
  • Product descriptioncis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine 98+%
  • Packaging10g
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA183059
  • Product descriptioncis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine 98+%
  • Packaging25g
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003081
  • Product descriptionKetoconazole 95.00%
  • Packaging100MG
  • Price$160.65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003081
  • Product descriptionKetoconazole 95.00%
  • Packaging1G
  • Price$1674.75
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4316
  • Product descriptionKetoconazole
  • Packaging500mg
  • Price$65
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-K0016-G001 Ketoconazole 99.0-101.0%(EP,Titration) 1g $71 2021-12-16 Buy
AHH API-1211 Ketocanazole 98% 250g $620 2021-12-16 Buy
AK Scientific F963 Ketoconazole 1g $21 2021-12-16 Buy
AK Scientific J94064 Ketoconazole 10g $75 2021-12-16 Buy
AK Scientific J94064 Ketoconazole 25g $135 2021-12-16 Buy
Alfa Aesar J67352 Ketoconazole, 2 mg/ml in methanol, sterile-filtered 1ml $47.9 2023-06-20 Buy
Alfa Aesar J67352 Ketoconazole, 2 mg/ml in methanol, sterile-filtered 5x1ml $150 2023-06-20 Buy
Alfa Aesar J63367 Ketoconazole, 98% 5g $212 2024-03-01 Buy
Alfa Aesar J63367 Ketoconazole, 98% 25g $698.65 2024-03-01 Buy
Ambeed A183059 cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine 98+% 1g $7 2021-12-16 Buy
Ambeed A183059 cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine 98+% 5g $29 2021-12-16 Buy
Ambeed A183059 cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine 98+% 10g $54 2021-12-16 Buy
Ambeed A183059 cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine 98+% 25g $68 2021-12-16 Buy
American Custom Chemicals Corporation API0003081 Ketoconazole 95.00% 100MG $160.65 2021-12-16 Buy
American Custom Chemicals Corporation API0003081 Ketoconazole 95.00% 1G $1674.75 2021-12-16 Buy
ApexBio Technology A4316 Ketoconazole 500mg $65 2021-12-16 Buy

Properties

Melting point :148-152 °C
Boiling point :753.4±60.0 °C(Predicted)
Density :1.4046 (rough estimate)
refractive index :-10.5 ° (C=0.4, CHCl3)
Flash point :9℃
storage temp. :2-8°C
solubility :methanol: soluble50mg/mL
pka :pKa 3.25/6.22(H2O,t =25,I=0.025) (Uncertain)
form :Off-white solid
color :white to light yellow
optical activity :[α]20/D -1 to 1°, c = 4 in methanol
Water Solubility :Soluble in DMSO, ethanol, chloroform, water, and methanol.
Merck :14,5302
BCS Class :2
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :XMAYWYJOQHXEEK-OZXSUGGESA-N
LogP :4.350
CAS DataBase Reference :65277-42-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P273 Avoid release to the environment.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Ketoconazole is an orally active broad spectrum antifungal agent that blocks ergosterol biosynthesis by inhibiting the fungal cytochrome P450 (CYP) isoform CYP51, also known as lanosterol 14α-demethylase. It potently inhibits the mammalian analog CYP51A1 (IC50 = 63.5 nM), as well as a variety of other CYP isoforms.

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