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ChemicalBook >> CAS DataBase List >> PF-06447475

PF-06447475

PF-06447475 price.
  • $25 - $1900
  • Product name: PF-06447475
  • CAS: 1527473-33-1
  • MF: C17H15N5O
  • MW: 305.33
  • EINECS:
  • MDL Number:MFCD28347838
  • Synonyms:PF-06447475;3-(4-morpholino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)benzonitrile;3-[4-(4-Morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-benzonitrile;3-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)benzonitrile;PF 06447475;PF06447475;CS-1734;PF-06447475, >98%;Benzonitrile, 3-[4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-
19 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product numberX3567
  • Product descriptionPF-06447475
  • Packaging50mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4906
  • Product descriptionPF-06447475
  • Packaging5mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4906
  • Product descriptionPF-06447475
  • Packaging10mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4906
  • Product descriptionPF-06447475
  • Packaging10mM(in 1mL DMSO)
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2546
  • Product descriptionPF-06447475 99%
  • Packaging25mg
  • Price$357.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFM126359
  • Product descriptionPF 06447475
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFM126359
  • Product descriptionPF 06447475
  • Packaging50mg
  • Price$297.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18375
  • Product descriptionPF-06447475 ≥98%
  • Packaging1mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18375
  • Product descriptionPF-06447475 ≥98%
  • Packaging5mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18375
  • Product descriptionPF-06447475 ≥98%
  • Packaging10mg
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18375
  • Product descriptionPF-06447475 ≥98%
  • Packaging25mg
  • Price$313
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM152433
  • Product description3-(4-Morpholino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)benzonitrile 98%
  • Packaging10mg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003302
  • Product descriptionPF-06447475 98+%
  • Packaging100mg
  • Price$222
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003302
  • Product descriptionPF-06447475 98+%
  • Packaging250mg
  • Price$399
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7971
  • Product descriptionPF-06447475 >98%
  • Packaging250mg
  • Price$1000
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7971
  • Product descriptionPF-06447475 >98%
  • Packaging1g
  • Price$1900
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X3567 PF-06447475 50mg $250 2021-12-16 Buy
ApexBio Technology B4906 PF-06447475 5mg $55 2021-12-16 Buy
ApexBio Technology B4906 PF-06447475 10mg $80 2021-12-16 Buy
ApexBio Technology B4906 PF-06447475 10mM(in 1mL DMSO) $80 2021-12-16 Buy
Axon Medchem Axon2546 PF-06447475 99% 25mg $357.5 2021-12-16 Buy
Biosynth Carbosynth FM126359 PF 06447475 10mg $85 2021-12-16 Buy
Biosynth Carbosynth FM126359 PF 06447475 50mg $297.5 2021-12-16 Buy
Cayman Chemical 18375 PF-06447475 ≥98% 1mg $25 2021-12-16 Buy
Cayman Chemical 18375 PF-06447475 ≥98% 5mg $75 2021-12-16 Buy
Cayman Chemical 18375 PF-06447475 ≥98% 10mg $138 2021-12-16 Buy
Cayman Chemical 18375 PF-06447475 ≥98% 25mg $313 2021-12-16 Buy
Chemenu CM152433 3-(4-Morpholino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)benzonitrile 98% 10mg $116 2021-12-16 Buy
Crysdot CD31003302 PF-06447475 98+% 100mg $222 2021-12-16 Buy
Crysdot CD31003302 PF-06447475 98+% 250mg $399 2021-12-16 Buy
DC Chemicals DC7971 PF-06447475 >98% 250mg $1000 2021-12-16 Buy
DC Chemicals DC7971 PF-06447475 >98% 1g $1900 2021-12-16 Buy

Properties

Melting point :>223°C (dec.)
Density :1.40±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble10mg/mL, clear
pka :12.96±0.50(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

PF-06447475 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2; IC50 = 3 nM), an enzyme genetically linked to Parkinson's disease that interacts with parkin, a ligase whose loss of function leads to dopaminergic cell death. PF-06447475 has been shown to attenuate α-synuclein-induced dopaminergic neurodegeneration and neuroinflammation in G2019S-LRRK2-expressing rats.