ChemicalBook CAS DataBase List 1-Butylpyrrolidine

1-Butylpyrrolidine synthesis

13synthesis methods

Product Name:1-Butylpyrrolidine
CAS Number:767-10-2
Molecular formula:C8H17N
Molecular Weight:127.23

The synthesis of 1-butylpyrrolidine and its derivatives (1-butylpyrrolidine with a little of 1-butenylpyrrolidines) was developed via a one-pot method from ammonia and 1,4-butandiol. Here, the product of 1-butylpyrrolidine was emphatically investigated, and the yield was 76% under the optimized conditions. Such a route was realized through successive N-alkylation using aqueous ammonia as the nitrogen source over the CuNiPd/ZSM-5 catalyst, which was prepared by a simple incipient wetness method. In this route, 1,4-butandiol not only participated in the formation of the N-heterocycle, but also acted as an alkylating reagent. This work offers a straightforward, economical route for 1-butylpyrrolidine and its derivatives.

One-pot synthesis of 1-butylpyrrolidine and its derivatives from aqueous ammonia and 1,4-butandiol over CuNiPd/ZSM-5 catalysts

626-67-5 Synthesis

626-67-5
213 suppliers
$15.00/25g

110-63-4 Synthesis

110-63-4
681 suppliers
$24.80/250g

767-10-2
106 suppliers
$60.00/100mg

Yield: 96%

Reaction Conditions:

with N-butylamine

Steps:

2 Preparation of N-(n-butyl)-pyrrolidine
EXAMPLE 2 Preparation of N-(n-butyl)-pyrrolidine 11.7 kg of butane-1,4-diol were reacted with 7.3 kg of n-butylamine similarly to Example 1. N-(n-butyl)-pyrrolidine was obtained in 96% yield.

References:

BASF Aktiengesellschaft US4910304, 1990, A

110-63-4 Synthesis

110-63-4
681 suppliers
$24.80/250g

71-36-3 Synthesis

71-36-3
1019 suppliers
$14.00/25mL

767-10-2
106 suppliers
$60.00/100mg

References

123-75-1 Synthesis

123-75-1
537 suppliers
$10.00/5g

123-72-8 Synthesis

123-72-8
400 suppliers
$12.32/25ML

767-10-2
106 suppliers
$60.00/100mg

References

123-75-1 Synthesis

123-75-1
537 suppliers
$10.00/5g

109-65-9 Synthesis

109-65-9
536 suppliers
$10.00/10g

767-10-2
106 suppliers
$60.00/100mg

References

123-75-1 Synthesis

123-75-1
537 suppliers
$10.00/5g

542-69-8
255 suppliers
$9.00/5g

767-10-2
106 suppliers
$60.00/100mg

References

1-Butylpyrrolidine Related Search:

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