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3-(4-FLUOROPHENYL)-3-PYRROLIDINOL synthesis

2synthesis methods
1-benzyl-3-(4-fluorophenyl)-3-pyrrolidinol

425663-33-8
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3-(4-FLUOROPHENYL)-3-PYRROLIDINOL

577986-35-7
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Yield:577986-35-7 100%

Reaction Conditions:

with hydrogen;palladium on activated charcoal in methanol at 20; under 2585.74 Torr; for 16 h;Hydrogenolysis;

References:

Ng, Howard P.;Karen, May;Bauman, John G.;Ghannam, Ameen;Islam, Imadul;Liang, Meina;Horuk, Richard;Hesselgesser, Joseph;Snider, R. Michael;Perez, H. Daniel;Morrissey, Michael M. [Journal of Medicinal Chemistry,1999,vol. 42,# 22,p. 4680 - 4694]

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