3-HYDROXY-5,6-DIPHENYL-1,2,4-TRIAZINE synthesis

12synthesis methods

Product Name:3-HYDROXY-5,6-DIPHENYL-1,2,4-TRIAZINE
CAS Number:4512-00-9
Molecular formula:C15H11N3O
Molecular Weight:249.27

37469-24-2 Synthesis

37469-24-2
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$60.00/100mg

4512-00-9
29 suppliers
$118.00/500mg

Yield:4512-00-9 91%

Reaction Conditions:

with tetrabromoglycoluril in ethanol at 40; for 0.166667 h;Green chemistry;Reagent/catalyst;

Steps:

General procedure for the oxidation of thioureas 1a - 6a to ureas 1b - 6b

General procedure: Tetrabromo and tetrachloroglycoluril, 0.4 mol, was added to a solution of 1 mol of 1a - 6a in 10 mL of ethanol or methanol (Table 1). During the addition, the mixture turned light yellow. It was stirred for 10 - 25 min at 40 °C until the yellow color disappeared and filtered from the precipitate of glycoluril, the filtrate was concentrated, and the solid product was filtered off and washed with water. The products were identified by comparing their physical properties and spectral characteristics with published data. The yields of 1b - 6b are given in Table 1.

References:

Arrous, S.;Boudebouz, I.;Parunov, I. V. [Russian Journal of Organic Chemistry,2019,vol. 55,# 12,p. 1874 - 1877][Zh. Org. Khim.,2019,vol. 55,# 12,p. 1883 - 1887,5]