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3-(tert-ButyldiMethylsilyl)Morphinone synthesis

5synthesis methods
18162-48-6 Synthesis
tert-Butyldimethylsilyl chloride

18162-48-6
652 suppliers
$9.00/5g

3-(tert-ButyldiMethylsilyl)Morphinone

91265-75-7
3 suppliers
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: 65 percent / tetrahydrofuran / 40 h / 25 °C
2: silver carbonate / benzene / 2 h / Heating

References:

Fang;Takemori;Portoghese [Journal of Medicinal Chemistry,1984,vol. 27,# 10,p. 1361 - 1363]